Characterization of a pluripotent stem cell-derived matrix with powerful osteoregenerative capabilities

Production of a safe and manufacturable material to mimic anabolic bone for tissue engineering has been hard to achieve to date. Here the authors use a mesenchymal stem cell line generated from induced pluripotent stem cells to produce osteogenic cell-matrix, displaying significant healing propertie...

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Autores principales:	Eoin P. McNeill, Suzanne Zeitouni, Simin Pan, Andrew Haskell, Michael Cesarek, Daniel Tahan, Bret H. Clough, Ulf Krause, Lauren K. Dobson, Mayra Garcia, Christopher Kung, Qingguo Zhao, W. Brian Saunders, Fei Liu, Roland Kaunas, Carl A. Gregory
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b65300d75d9744b7bb5511825de6cee1
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spelling	oai:doaj.org-article:b65300d75d9744b7bb5511825de6cee12021-12-02T17:39:44ZCharacterization of a pluripotent stem cell-derived matrix with powerful osteoregenerative capabilities10.1038/s41467-020-16646-22041-1723https://doaj.org/article/b65300d75d9744b7bb5511825de6cee12020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16646-2https://doaj.org/toc/2041-1723Production of a safe and manufacturable material to mimic anabolic bone for tissue engineering has been hard to achieve to date. Here the authors use a mesenchymal stem cell line generated from induced pluripotent stem cells to produce osteogenic cell-matrix, displaying significant healing properties in mice.Eoin P. McNeillSuzanne ZeitouniSimin PanAndrew HaskellMichael CesarekDaniel TahanBret H. CloughUlf KrauseLauren K. DobsonMayra GarciaChristopher KungQingguo ZhaoW. Brian SaundersFei LiuRoland KaunasCarl A. GregoryNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Eoin P. McNeill Suzanne Zeitouni Simin Pan Andrew Haskell Michael Cesarek Daniel Tahan Bret H. Clough Ulf Krause Lauren K. Dobson Mayra Garcia Christopher Kung Qingguo Zhao W. Brian Saunders Fei Liu Roland Kaunas Carl A. Gregory Characterization of a pluripotent stem cell-derived matrix with powerful osteoregenerative capabilities
description	Production of a safe and manufacturable material to mimic anabolic bone for tissue engineering has been hard to achieve to date. Here the authors use a mesenchymal stem cell line generated from induced pluripotent stem cells to produce osteogenic cell-matrix, displaying significant healing properties in mice.
format	article
author	Eoin P. McNeill Suzanne Zeitouni Simin Pan Andrew Haskell Michael Cesarek Daniel Tahan Bret H. Clough Ulf Krause Lauren K. Dobson Mayra Garcia Christopher Kung Qingguo Zhao W. Brian Saunders Fei Liu Roland Kaunas Carl A. Gregory
author_facet	Eoin P. McNeill Suzanne Zeitouni Simin Pan Andrew Haskell Michael Cesarek Daniel Tahan Bret H. Clough Ulf Krause Lauren K. Dobson Mayra Garcia Christopher Kung Qingguo Zhao W. Brian Saunders Fei Liu Roland Kaunas Carl A. Gregory
author_sort	Eoin P. McNeill
title	Characterization of a pluripotent stem cell-derived matrix with powerful osteoregenerative capabilities
title_short	Characterization of a pluripotent stem cell-derived matrix with powerful osteoregenerative capabilities
title_full	Characterization of a pluripotent stem cell-derived matrix with powerful osteoregenerative capabilities
title_fullStr	Characterization of a pluripotent stem cell-derived matrix with powerful osteoregenerative capabilities
title_full_unstemmed	Characterization of a pluripotent stem cell-derived matrix with powerful osteoregenerative capabilities
title_sort	characterization of a pluripotent stem cell-derived matrix with powerful osteoregenerative capabilities
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/b65300d75d9744b7bb5511825de6cee1
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Characterization of a pluripotent stem cell-derived matrix with powerful osteoregenerative capabilities

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