Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.

Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.

<h4>Background</h4>Altered expression of DNA polymerase beta (Pol beta) has been documented in a large percentage of human tumors. However, tumor prevalence or predisposition resulting from Pol beta over-expression has not yet been evaluated in a mouse model.<h4>Methodology/princip...

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Autores principales: Katsuhiko Yoshizawa, Elena Jelezcova, Ashley R Brown, Julie F Foley, Abraham Nyska, Xiangli Cui, Lorne J Hofseth, Robert M Maronpot, Samuel H Wilson, Antonia R Sepulveda, Robert W Sobol
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/b65921f2bf664cfdb0ae6713d59bfa0a
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