Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development

De novo DNA methylation is carried out by DNMT3A and DNMT3B, but the distinct functions of these two enzymes is poorly understood. Here the authors present a comprehensive, genome-wide identification of target sites for de novo DNA methylation by the DNMT3A and DNMT3B in mouse ES cells and embryos,...

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Auteurs principaux: Masaki Yagi, Mio Kabata, Akito Tanaka, Tomoyo Ukai, Sho Ohta, Kazuhiko Nakabayashi, Masahito Shimizu, Kenichiro Hata, Alexander Meissner, Takuya Yamamoto, Yasuhiro Yamada
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/b65b6e33e3a14ce7b532093c4f2b9276
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