Research Progress on Cell Membrane-Coated Biomimetic Delivery Systems

Cell membrane-coated biomimetic nanoplatforms have many inherent properties, such as bio-interfacing abilities, self-identification, and signal transduction, which enable the biomimetic delivery system to escape immune clearance and opsonization. This can also maximize the drug delivery efficiency o...

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Autores principales: Mengyu Guo, Chenjie Xia, Yu Wu, Nong Zhou, Zhipeng Chen, Weidong Li
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Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/b66aac8c48884235a7e2b31a84faeb74
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spelling oai:doaj.org-article:b66aac8c48884235a7e2b31a84faeb742021-11-16T07:40:13ZResearch Progress on Cell Membrane-Coated Biomimetic Delivery Systems2296-418510.3389/fbioe.2021.772522https://doaj.org/article/b66aac8c48884235a7e2b31a84faeb742021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fbioe.2021.772522/fullhttps://doaj.org/toc/2296-4185Cell membrane-coated biomimetic nanoplatforms have many inherent properties, such as bio-interfacing abilities, self-identification, and signal transduction, which enable the biomimetic delivery system to escape immune clearance and opsonization. This can also maximize the drug delivery efficiency of synthetic nanoparticles (NPs) and functional cell membranes. As a new type of delivery system, cell membrane-coated biomimetic delivery systems have broadened the prospects for biomedical applications. In this review, we summarize research progress on cell membrane biomimetic technology from three aspects, including sources of membrane, modifications, and applications, then analyze their limitations and propose future research directions.Mengyu GuoMengyu GuoChenjie XiaChenjie XiaYu WuYu WuNong ZhouZhipeng ChenZhipeng ChenWeidong LiWeidong LiFrontiers Media S.A.articlecell membranebiomimeticdrug deliverynanomedicinenanobiotechnologyBiotechnologyTP248.13-248.65ENFrontiers in Bioengineering and Biotechnology, Vol 9 (2021)
institution DOAJ
collection DOAJ
language EN
topic cell membrane
biomimetic
drug delivery
nanomedicine
nanobiotechnology
Biotechnology
TP248.13-248.65
spellingShingle cell membrane
biomimetic
drug delivery
nanomedicine
nanobiotechnology
Biotechnology
TP248.13-248.65
Mengyu Guo
Mengyu Guo
Chenjie Xia
Chenjie Xia
Yu Wu
Yu Wu
Nong Zhou
Zhipeng Chen
Zhipeng Chen
Weidong Li
Weidong Li
Research Progress on Cell Membrane-Coated Biomimetic Delivery Systems
description Cell membrane-coated biomimetic nanoplatforms have many inherent properties, such as bio-interfacing abilities, self-identification, and signal transduction, which enable the biomimetic delivery system to escape immune clearance and opsonization. This can also maximize the drug delivery efficiency of synthetic nanoparticles (NPs) and functional cell membranes. As a new type of delivery system, cell membrane-coated biomimetic delivery systems have broadened the prospects for biomedical applications. In this review, we summarize research progress on cell membrane biomimetic technology from three aspects, including sources of membrane, modifications, and applications, then analyze their limitations and propose future research directions.
format article
author Mengyu Guo
Mengyu Guo
Chenjie Xia
Chenjie Xia
Yu Wu
Yu Wu
Nong Zhou
Zhipeng Chen
Zhipeng Chen
Weidong Li
Weidong Li
author_facet Mengyu Guo
Mengyu Guo
Chenjie Xia
Chenjie Xia
Yu Wu
Yu Wu
Nong Zhou
Zhipeng Chen
Zhipeng Chen
Weidong Li
Weidong Li
author_sort Mengyu Guo
title Research Progress on Cell Membrane-Coated Biomimetic Delivery Systems
title_short Research Progress on Cell Membrane-Coated Biomimetic Delivery Systems
title_full Research Progress on Cell Membrane-Coated Biomimetic Delivery Systems
title_fullStr Research Progress on Cell Membrane-Coated Biomimetic Delivery Systems
title_full_unstemmed Research Progress on Cell Membrane-Coated Biomimetic Delivery Systems
title_sort research progress on cell membrane-coated biomimetic delivery systems
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/b66aac8c48884235a7e2b31a84faeb74
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