Allelic diversity of the Plasmodium falciparum erythrocyte membrane protein 1 entails variant-specific red cell surface epitopes.

Allelic diversity of the Plasmodium falciparum erythrocyte membrane protein 1 entails variant-specific red cell surface epitopes.

The clonally variant Plasmodium falciparum PfEMP1 adhesin is a virulence factor and a prime target of humoral immunity. It is encoded by a repertoire of functionally differentiated var genes, which display architectural diversity and allelic polymorphism. Their serological relationship is key to und...

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Autores principales: Inès Vigan-Womas, Micheline Guillotte, Alexandre Juillerat, Cindy Vallieres, Anita Lewit-Bentley, Adama Tall, Laurence Baril, Graham A Bentley, Odile Mercereau-Puijalon
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/b66eaeb47b1f4584836b810bf1c4af48
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