Modulation of AggR levels reveals features of virulence regulation in enteroaggregative E. coli

Studying Enteroaggregative E. coli (EAEC), Prieto et al have found that the 3′UTR of the gene that encodes the transcriptional activator AggR, regulates aggR transcript stability. They further demonstrate that enhanced levels of AggR leads to increased motility and virulence and identify novel AggR–...

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Autores principales:	Alejandro Prieto, Manuel Bernabeu, José Francisco Sánchez-Herrero, Anna Pérez-Bosque, Lluïsa Miró, Christine Bäuerl, Carmen Collado, Mário Hüttener, Antonio Juárez
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/b678a957356c4e07a1f2cb6003d6d7fe
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spelling	oai:doaj.org-article:b678a957356c4e07a1f2cb6003d6d7fe2021-11-21T12:08:16ZModulation of AggR levels reveals features of virulence regulation in enteroaggregative E. coli10.1038/s42003-021-02820-92399-3642https://doaj.org/article/b678a957356c4e07a1f2cb6003d6d7fe2021-11-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02820-9https://doaj.org/toc/2399-3642Studying Enteroaggregative E. coli (EAEC), Prieto et al have found that the 3′UTR of the gene that encodes the transcriptional activator AggR, regulates aggR transcript stability. They further demonstrate that enhanced levels of AggR leads to increased motility and virulence and identify novel AggR–regulated genes that may be important for EAEC virulence.Alejandro PrietoManuel BernabeuJosé Francisco Sánchez-HerreroAnna Pérez-BosqueLluïsa MiróChristine BäuerlCarmen ColladoMário HüttenerAntonio JuárezNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Alejandro Prieto Manuel Bernabeu José Francisco Sánchez-Herrero Anna Pérez-Bosque Lluïsa Miró Christine Bäuerl Carmen Collado Mário Hüttener Antonio Juárez Modulation of AggR levels reveals features of virulence regulation in enteroaggregative E. coli
description	Studying Enteroaggregative E. coli (EAEC), Prieto et al have found that the 3′UTR of the gene that encodes the transcriptional activator AggR, regulates aggR transcript stability. They further demonstrate that enhanced levels of AggR leads to increased motility and virulence and identify novel AggR–regulated genes that may be important for EAEC virulence.
format	article
author	Alejandro Prieto Manuel Bernabeu José Francisco Sánchez-Herrero Anna Pérez-Bosque Lluïsa Miró Christine Bäuerl Carmen Collado Mário Hüttener Antonio Juárez
author_facet	Alejandro Prieto Manuel Bernabeu José Francisco Sánchez-Herrero Anna Pérez-Bosque Lluïsa Miró Christine Bäuerl Carmen Collado Mário Hüttener Antonio Juárez
author_sort	Alejandro Prieto
title	Modulation of AggR levels reveals features of virulence regulation in enteroaggregative E. coli
title_short	Modulation of AggR levels reveals features of virulence regulation in enteroaggregative E. coli
title_full	Modulation of AggR levels reveals features of virulence regulation in enteroaggregative E. coli
title_fullStr	Modulation of AggR levels reveals features of virulence regulation in enteroaggregative E. coli
title_full_unstemmed	Modulation of AggR levels reveals features of virulence regulation in enteroaggregative E. coli
title_sort	modulation of aggr levels reveals features of virulence regulation in enteroaggregative e. coli
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b678a957356c4e07a1f2cb6003d6d7fe
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Modulation of AggR levels reveals features of virulence regulation in enteroaggregative E. coli

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