Founder BRCA1/BRCA2/PALB2 pathogenic variants in French-Canadian breast cancer cases and controls
Abstract Inherited germline pathogenic variants are responsible for ~5% of breast cancer globally. Through rapid expansion and isolation since immigration in the early 17th century, French Canadians are a relatively genetically homogenous founder population and therefore represent a unique demograph...
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Main Authors: | Supriya Behl, Nancy Hamel, Manon de Ladurantaye, Stéphanie Lepage, Réjean Lapointe, Anne-Marie Mes-Masson, William D. Foulkes |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Online Access: | https://doaj.org/article/b67ddaa5e9f64dcabd8141ee8ac1639b |
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