The proteasome 19S cap and its ubiquitin receptors provide a versatile recognition platform for substrates
Ubiquitylated proteins are degraded by the proteasome and the three proteasome subunits Rpn10, Rpn13 and Rpn1 recognize ubiquitin chains. Here the authors employ biochemical and kinetic assays and characterise the ubiquitin chain type specificities of these three ubiquitin receptors.
Guardado en:
Autores principales: | Kirby Martinez-Fonts, Caroline Davis, Takuya Tomita, Suzanne Elsasser, Andrew R. Nager, Yuan Shi, Daniel Finley, Andreas Matouschek |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/b6829197ab4442dc88d9ed892b9626e3 |
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