The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression

In both focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN), kidney injury is characterised by the invasion of glomerular tufts by parietal epithelial cells (PECs). Here Lazareth et al. identify the tetraspanin CD9 as a key regulator of PEC migration, and find its upreg...

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Autores principales:	Hélène Lazareth, Carole Henique, Olivia Lenoir, Victor G. Puelles, Martin Flamant, Guillaume Bollée, Cécile Fligny, Marine Camus, Lea Guyonnet, Corinne Millien, François Gaillard, Anna Chipont, Blaise Robin, Sylvie Fabrega, Neeraj Dhaun, Eric Camerer, Oliver Kretz, Florian Grahammer, Fabian Braun, Tobias B. Huber, Dominique Nochy, Chantal Mandet, Patrick Bruneval, Laurent Mesnard, Eric Thervet, Alexandre Karras, François Le Naour, Eric Rubinstein, Claude Boucheix, Antigoni Alexandrou, Marcus J. Moeller, Cédric Bouzigues, Pierre-Louis Tharaux
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b682a5c3bcb44d6ba72e2b6a4e2372c3
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spelling	oai:doaj.org-article:b682a5c3bcb44d6ba72e2b6a4e2372c32021-12-02T15:36:00ZThe tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression10.1038/s41467-019-11013-22041-1723https://doaj.org/article/b682a5c3bcb44d6ba72e2b6a4e2372c32019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11013-2https://doaj.org/toc/2041-1723In both focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN), kidney injury is characterised by the invasion of glomerular tufts by parietal epithelial cells (PECs). Here Lazareth et al. identify the tetraspanin CD9 as a key regulator of PEC migration, and find its upregulation in FSGS and CGN contributes to kidney injury in both diseases.Hélène LazarethCarole HeniqueOlivia LenoirVictor G. PuellesMartin FlamantGuillaume BolléeCécile FlignyMarine CamusLea GuyonnetCorinne MillienFrançois GaillardAnna ChipontBlaise RobinSylvie FabregaNeeraj DhaunEric CamererOliver KretzFlorian GrahammerFabian BraunTobias B. HuberDominique NochyChantal MandetPatrick BrunevalLaurent MesnardEric ThervetAlexandre KarrasFrançois Le NaourEric RubinsteinClaude BoucheixAntigoni AlexandrouMarcus J. MoellerCédric BouziguesPierre-Louis TharauxNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hélène Lazareth Carole Henique Olivia Lenoir Victor G. Puelles Martin Flamant Guillaume Bollée Cécile Fligny Marine Camus Lea Guyonnet Corinne Millien François Gaillard Anna Chipont Blaise Robin Sylvie Fabrega Neeraj Dhaun Eric Camerer Oliver Kretz Florian Grahammer Fabian Braun Tobias B. Huber Dominique Nochy Chantal Mandet Patrick Bruneval Laurent Mesnard Eric Thervet Alexandre Karras François Le Naour Eric Rubinstein Claude Boucheix Antigoni Alexandrou Marcus J. Moeller Cédric Bouzigues Pierre-Louis Tharaux The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression
description	In both focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN), kidney injury is characterised by the invasion of glomerular tufts by parietal epithelial cells (PECs). Here Lazareth et al. identify the tetraspanin CD9 as a key regulator of PEC migration, and find its upregulation in FSGS and CGN contributes to kidney injury in both diseases.
format	article
author	Hélène Lazareth Carole Henique Olivia Lenoir Victor G. Puelles Martin Flamant Guillaume Bollée Cécile Fligny Marine Camus Lea Guyonnet Corinne Millien François Gaillard Anna Chipont Blaise Robin Sylvie Fabrega Neeraj Dhaun Eric Camerer Oliver Kretz Florian Grahammer Fabian Braun Tobias B. Huber Dominique Nochy Chantal Mandet Patrick Bruneval Laurent Mesnard Eric Thervet Alexandre Karras François Le Naour Eric Rubinstein Claude Boucheix Antigoni Alexandrou Marcus J. Moeller Cédric Bouzigues Pierre-Louis Tharaux
author_facet	Hélène Lazareth Carole Henique Olivia Lenoir Victor G. Puelles Martin Flamant Guillaume Bollée Cécile Fligny Marine Camus Lea Guyonnet Corinne Millien François Gaillard Anna Chipont Blaise Robin Sylvie Fabrega Neeraj Dhaun Eric Camerer Oliver Kretz Florian Grahammer Fabian Braun Tobias B. Huber Dominique Nochy Chantal Mandet Patrick Bruneval Laurent Mesnard Eric Thervet Alexandre Karras François Le Naour Eric Rubinstein Claude Boucheix Antigoni Alexandrou Marcus J. Moeller Cédric Bouzigues Pierre-Louis Tharaux
author_sort	Hélène Lazareth
title	The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression
title_short	The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression
title_full	The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression
title_fullStr	The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression
title_full_unstemmed	The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression
title_sort	tetraspanin cd9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b682a5c3bcb44d6ba72e2b6a4e2372c3
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The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression

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