The (re)discovery of tumor-intrinsic determinants of immune sensitivity by functional genetic screens
Functional genetic screens by CRISPR-Cas9 allow for the unbiased discovery of proteins causally involved in complex biological processes. In recent years, this approach has been used by multiple laboratories to uncover a range of tumor cell regulators determining immune sensitivity. In this review,...
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Autores principales: | D.W. Vredevoogd, G. Apriamashvili, D.S. Peeper |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/b6875c84503849e3804aa00e191cb1ad |
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