The (re)discovery of tumor-intrinsic determinants of immune sensitivity by functional genetic screens

Functional genetic screens by CRISPR-Cas9 allow for the unbiased discovery of proteins causally involved in complex biological processes. In recent years, this approach has been used by multiple laboratories to uncover a range of tumor cell regulators determining immune sensitivity. In this review,...

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Bibliographic Details
Main Authors: D.W. Vredevoogd, G. Apriamashvili, D.S. Peeper
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/b6875c84503849e3804aa00e191cb1ad
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