Evolution of tertiary structure of viral RNA dependent polymerases.

Evolution of tertiary structure of viral RNA dependent polymerases.

Viral RNA dependent polymerases (vRdPs) are present in all RNA viruses; unfortunately, their sequence similarity is too low for phylogenetic studies. Nevertheless, vRdP protein structures are remarkably conserved. In this study, we used the structural similarity of vRdPs to reconstruct their evoluti...

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Autores principales: Jiří Černý, Barbora Černá Bolfíková, James J Valdés, Libor Grubhoffer, Daniel Růžek
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b695d498de1946d0943aa48e3d58a4c4
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