Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion

Infection of mice with Citrobacter rodentium is a common model of infection with attaching-and-effacing pathogens. Here, Connolly et al. analyse the transcriptome of C. rodentium during mouse infection, showing host-induced coordinated upregulation of virulence factors and 1,2-propanediol metabolism...

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Autores principales:	James P. R. Connolly, Sabrina L. Slater, Nicky O’Boyle, Robert J. Goldstone, Valerie F. Crepin, David Ruano-Gallego, Pawel Herzyk, David G. E. Smith, Gillian R. Douce, Gad Frankel, Andrew J. Roe
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b6965592be8f4c16ab3622e53a3e14e5
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spelling	oai:doaj.org-article:b6965592be8f4c16ab3622e53a3e14e52021-12-02T15:34:41ZHost-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion10.1038/s41467-018-06701-42041-1723https://doaj.org/article/b6965592be8f4c16ab3622e53a3e14e52018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06701-4https://doaj.org/toc/2041-1723Infection of mice with Citrobacter rodentium is a common model of infection with attaching-and-effacing pathogens. Here, Connolly et al. analyse the transcriptome of C. rodentium during mouse infection, showing host-induced coordinated upregulation of virulence factors and 1,2-propanediol metabolism.James P. R. ConnollySabrina L. SlaterNicky O’BoyleRobert J. GoldstoneValerie F. CrepinDavid Ruano-GallegoPawel HerzykDavid G. E. SmithGillian R. DouceGad FrankelAndrew J. RoeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q James P. R. Connolly Sabrina L. Slater Nicky O’Boyle Robert J. Goldstone Valerie F. Crepin David Ruano-Gallego Pawel Herzyk David G. E. Smith Gillian R. Douce Gad Frankel Andrew J. Roe Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion
description	Infection of mice with Citrobacter rodentium is a common model of infection with attaching-and-effacing pathogens. Here, Connolly et al. analyse the transcriptome of C. rodentium during mouse infection, showing host-induced coordinated upregulation of virulence factors and 1,2-propanediol metabolism.
format	article
author	James P. R. Connolly Sabrina L. Slater Nicky O’Boyle Robert J. Goldstone Valerie F. Crepin David Ruano-Gallego Pawel Herzyk David G. E. Smith Gillian R. Douce Gad Frankel Andrew J. Roe
author_facet	James P. R. Connolly Sabrina L. Slater Nicky O’Boyle Robert J. Goldstone Valerie F. Crepin David Ruano-Gallego Pawel Herzyk David G. E. Smith Gillian R. Douce Gad Frankel Andrew J. Roe
author_sort	James P. R. Connolly
title	Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion
title_short	Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion
title_full	Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion
title_fullStr	Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion
title_full_unstemmed	Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion
title_sort	host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/b6965592be8f4c16ab3622e53a3e14e5
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Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion

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