Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion

Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion

Infection of mice with Citrobacter rodentium is a common model of infection with attaching-and-effacing pathogens. Here, Connolly et al. analyse the transcriptome of C. rodentium during mouse infection, showing host-induced coordinated upregulation of virulence factors and 1,2-propanediol metabolism...

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Autores principales: James P. R. Connolly, Sabrina L. Slater, Nicky O’Boyle, Robert J. Goldstone, Valerie F. Crepin, David Ruano-Gallego, Pawel Herzyk, David G. E. Smith, Gillian R. Douce, Gad Frankel, Andrew J. Roe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/b6965592be8f4c16ab3622e53a3e14e5
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