Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings

Medium-sized ring systems are common in natural products, however their synthesis is challenging, largely due to entropic factors. Here the authors report a radical-based method for the synthesis of medium to large functionalized, carbon or heterocyclic scaffolds.

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Autores principales:	Lei Li, Zhong-Liang Li, Fu-Li Wang, Zhen Guo, Yong-Feng Cheng, Na Wang, Xiao-Wu Dong, Chao Fang, Jingjiang Liu, Chunhui Hou, Bin Tan, Xin-Yuan Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b698f683d92844d7b96b0fb27ba6934b
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spelling	oai:doaj.org-article:b698f683d92844d7b96b0fb27ba6934b2021-12-02T14:40:12ZRadical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings10.1038/ncomms138522041-1723https://doaj.org/article/b698f683d92844d7b96b0fb27ba6934b2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13852https://doaj.org/toc/2041-1723Medium-sized ring systems are common in natural products, however their synthesis is challenging, largely due to entropic factors. Here the authors report a radical-based method for the synthesis of medium to large functionalized, carbon or heterocyclic scaffolds.Lei LiZhong-Liang LiFu-Li WangZhen GuoYong-Feng ChengNa WangXiao-Wu DongChao FangJingjiang LiuChunhui HouBin TanXin-Yuan LiuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lei Li Zhong-Liang Li Fu-Li Wang Zhen Guo Yong-Feng Cheng Na Wang Xiao-Wu Dong Chao Fang Jingjiang Liu Chunhui Hou Bin Tan Xin-Yuan Liu Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings
description	Medium-sized ring systems are common in natural products, however their synthesis is challenging, largely due to entropic factors. Here the authors report a radical-based method for the synthesis of medium to large functionalized, carbon or heterocyclic scaffolds.
format	article
author	Lei Li Zhong-Liang Li Fu-Li Wang Zhen Guo Yong-Feng Cheng Na Wang Xiao-Wu Dong Chao Fang Jingjiang Liu Chunhui Hou Bin Tan Xin-Yuan Liu
author_facet	Lei Li Zhong-Liang Li Fu-Li Wang Zhen Guo Yong-Feng Cheng Na Wang Xiao-Wu Dong Chao Fang Jingjiang Liu Chunhui Hou Bin Tan Xin-Yuan Liu
author_sort	Lei Li
title	Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings
title_short	Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings
title_full	Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings
title_fullStr	Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings
title_full_unstemmed	Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings
title_sort	radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/b698f683d92844d7b96b0fb27ba6934b
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Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings

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