Structural basis for divergent C–H hydroxylation selectivity in two Rieske oxygenases

Rieske oxygenases are iron-dependent enzymes that catalyse C–H mono- and dihydroxylation reactions. Here, the authors characterise two cyanobacterial Rieske oxygenases, SxtT and GxtA that are involved in the biosynthesis of paralytic shellfish toxins and determine their substrate free and saxitoxin...

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Auteurs principaux: April L. Lukowski, Jianxin Liu, Jennifer Bridwell-Rabb, Alison R. H. Narayan
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/b69e299e06b4475ab6229373dc78b546
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