Efficacy of Shenqi Jiangtang Granules-Assisted Western Medi-cine in the Treatment of Gestational Diabetes Mellitus (GDM)

Background: We aimed to investigate the efficacy of Shenqi Jiangtang granules-assisted Western medicine in the treatment of gestational diabetes mellitus (GDM). Methods: A total of 147 patients with GDM treated in Qilu Hospital of Shandong University from Jan 2018 to Apr 2019 were enrolled. They...

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Autores principales:	Juan Tang, Li Fan, Chunlei Lv, Runjie Wan, Jianjian Liu, Xiaoyan Liu
Formato:	article
Lenguaje:	EN
Publicado:	Tehran University of Medical Sciences 2021
Materias:	Shenqi Jiangtang granules Gestational diabetes mellitus Clinical efficacy Adverse pregnancy outcome Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/b6ab49f39159447e874f758c7da4415c
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spelling	oai:doaj.org-article:b6ab49f39159447e874f758c7da4415c2021-12-02T18:23:25ZEfficacy of Shenqi Jiangtang Granules-Assisted Western Medi-cine in the Treatment of Gestational Diabetes Mellitus (GDM)2251-60852251-6093https://doaj.org/article/b6ab49f39159447e874f758c7da4415c2021-10-01T00:00:00Zhttps://ijph.tums.ac.ir/index.php/ijph/article/view/24175https://doaj.org/toc/2251-6085https://doaj.org/toc/2251-6093 Background: We aimed to investigate the efficacy of Shenqi Jiangtang granules-assisted Western medicine in the treatment of gestational diabetes mellitus (GDM). Methods: A total of 147 patients with GDM treated in Qilu Hospital of Shandong University from Jan 2018 to Apr 2019 were enrolled. They were randomly divided into traditional Chinese medicine (TCM) combined with Western medicine group, Western medicine group and control group. The control group was treated with exercise combined with diet therapy, and the Western medicine group was additionally treated with metformin tablets. The TCM combined with Western medicine group was additionally treated with Shenqi Jiangtang granules. Results: After treatment, the levels of 10 indicators in the three groups were lower than those before treatment (P < 0.05). These indicators were the lowest in the TCM combined with Western medicine group. However, high-density lipoprotein cholesterol (HDL-C), glutathione peroxidase (GSH-PX) and superoxide dismutase (SOD) after treatment increased in the three groups compared with those before treatment (P < 0.05), which was the most obvious in the TCM combined with Western medicine group. After treatment, the number of patients with natural delivery in the TCM combined with Western medicine group was the largest. The incidences of complications in pregnant women, fetuses and newborns were the lowest in the TCM combined with Western medicine group. Conclusion: Application of Shenqi Jiangtang granules-assisted Western medicine in patients with GDM can effectively control blood glucose and lipid levels, enhance antioxidant capacity, reduce the levels of inflammatory cytokines and decrease the incidence of adverse pregnancy outcomes. Juan TangLi FanChunlei LvRunjie WanJianjian LiuXiaoyan LiuTehran University of Medical SciencesarticleShenqi Jiangtang granulesGestational diabetes mellitusClinical efficacyAdverse pregnancy outcomePublic aspects of medicineRA1-1270ENIranian Journal of Public Health, Vol 50, Iss 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Shenqi Jiangtang granules Gestational diabetes mellitus Clinical efficacy Adverse pregnancy outcome Public aspects of medicine RA1-1270
spellingShingle	Shenqi Jiangtang granules Gestational diabetes mellitus Clinical efficacy Adverse pregnancy outcome Public aspects of medicine RA1-1270 Juan Tang Li Fan Chunlei Lv Runjie Wan Jianjian Liu Xiaoyan Liu Efficacy of Shenqi Jiangtang Granules-Assisted Western Medi-cine in the Treatment of Gestational Diabetes Mellitus (GDM)
description	Background: We aimed to investigate the efficacy of Shenqi Jiangtang granules-assisted Western medicine in the treatment of gestational diabetes mellitus (GDM). Methods: A total of 147 patients with GDM treated in Qilu Hospital of Shandong University from Jan 2018 to Apr 2019 were enrolled. They were randomly divided into traditional Chinese medicine (TCM) combined with Western medicine group, Western medicine group and control group. The control group was treated with exercise combined with diet therapy, and the Western medicine group was additionally treated with metformin tablets. The TCM combined with Western medicine group was additionally treated with Shenqi Jiangtang granules. Results: After treatment, the levels of 10 indicators in the three groups were lower than those before treatment (P < 0.05). These indicators were the lowest in the TCM combined with Western medicine group. However, high-density lipoprotein cholesterol (HDL-C), glutathione peroxidase (GSH-PX) and superoxide dismutase (SOD) after treatment increased in the three groups compared with those before treatment (P < 0.05), which was the most obvious in the TCM combined with Western medicine group. After treatment, the number of patients with natural delivery in the TCM combined with Western medicine group was the largest. The incidences of complications in pregnant women, fetuses and newborns were the lowest in the TCM combined with Western medicine group. Conclusion: Application of Shenqi Jiangtang granules-assisted Western medicine in patients with GDM can effectively control blood glucose and lipid levels, enhance antioxidant capacity, reduce the levels of inflammatory cytokines and decrease the incidence of adverse pregnancy outcomes.
format	article
author	Juan Tang Li Fan Chunlei Lv Runjie Wan Jianjian Liu Xiaoyan Liu
author_facet	Juan Tang Li Fan Chunlei Lv Runjie Wan Jianjian Liu Xiaoyan Liu
author_sort	Juan Tang
title	Efficacy of Shenqi Jiangtang Granules-Assisted Western Medi-cine in the Treatment of Gestational Diabetes Mellitus (GDM)
title_short	Efficacy of Shenqi Jiangtang Granules-Assisted Western Medi-cine in the Treatment of Gestational Diabetes Mellitus (GDM)
title_full	Efficacy of Shenqi Jiangtang Granules-Assisted Western Medi-cine in the Treatment of Gestational Diabetes Mellitus (GDM)
title_fullStr	Efficacy of Shenqi Jiangtang Granules-Assisted Western Medi-cine in the Treatment of Gestational Diabetes Mellitus (GDM)
title_full_unstemmed	Efficacy of Shenqi Jiangtang Granules-Assisted Western Medi-cine in the Treatment of Gestational Diabetes Mellitus (GDM)
title_sort	efficacy of shenqi jiangtang granules-assisted western medi-cine in the treatment of gestational diabetes mellitus (gdm)
publisher	Tehran University of Medical Sciences
publishDate	2021
url	https://doaj.org/article/b6ab49f39159447e874f758c7da4415c
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Efficacy of Shenqi Jiangtang Granules-Assisted Western Medi-cine in the Treatment of Gestational Diabetes Mellitus (GDM)

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