Digital analysis of flap parameter accuracy and objective assessment of opaque bubble layer in femtosecond laser-assisted LASIK: a novel technique

A John Kanellopoulos,1,2 George Asimellis11Laservision Eye Institute, Athens, Greece; 2New York University School of Medicine, New York, NY, USABackground: The purpose of this study was to determine flap parameter accuracy, extent of the opaque bubble layer, and incidence of skip lines in femtosecon...

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Autores principales:	Kanellopoulos AJ, Asimellis G
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/b6bd35c2d49f49ca832fa7491e87c10c
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spelling	oai:doaj.org-article:b6bd35c2d49f49ca832fa7491e87c10c2021-12-02T02:35:26ZDigital analysis of flap parameter accuracy and objective assessment of opaque bubble layer in femtosecond laser-assisted LASIK: a novel technique1177-54671177-5483https://doaj.org/article/b6bd35c2d49f49ca832fa7491e87c10c2013-02-01T00:00:00Zhttp://www.dovepress.com/digital-analysis-of-flap-parameter-accuracy-and-objective-assessment-o-a12218https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483A John Kanellopoulos,1,2 George Asimellis11Laservision Eye Institute, Athens, Greece; 2New York University School of Medicine, New York, NY, USABackground: The purpose of this study was to determine flap parameter accuracy, extent of the opaque bubble layer, and incidence of skip lines in femtosecond laser-assisted stromal in situ keratomileusis (LASIK) using the WaveLight&reg; FS200 laser and optoelectronic clinical measurements.Methods: Images from 101 flaps were automatically recorded during consecutive routine LASIK procedures performed using the WaveLight FS200 femtosecond laser and the EX500 excimer laser. Digital processing of these images was used to evaluate objectively the diameter of FS200-created flaps, by comparing planned versus achieved procedures and to evaluate the incidence and extent (area) of the opaque bubble layer.Results: The intended flap diameters were between 8.00 mm and 9.50 mm. The achieved flap diameters showed extremely high precision, and were on average -0.16 &plusmn; 0.04 mm smaller for a 8.00 mm intended flap diameter, -0.12 &plusmn; 0.03 mm smaller for a 8.50 mm flap, and up +0.06 &plusmn; 0.06 mm wider for a 9.50 mm flap. With an average flap area of 72.4 mm2, the mean area of the opaque bubble layer (4.1 &plusmn; 4.3 [range 0&ndash;14.34] mm2) corresponded to a 6% opaque bubble layer-to-flap area. Specifically, 80% of the femtosecond-created flaps had an essentially zero opaque bubble layer (&lt;2.7% of the flap area).Conclusion: In our clinical experience, flaps created using FS200 and this novel highly objective assessment technique demonstrate both precision and reproducibility. The incidence of opaque bubble layer was minimal.Keywords: femtosecond laser precision, bladeless laser-assisted stromal in situ keratomileusis, corneal flap diameter, opaque bubble layer, skip lines, WaveLight FS200Kanellopoulos AJAsimellis GDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 343-351 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Kanellopoulos AJ Asimellis G Digital analysis of flap parameter accuracy and objective assessment of opaque bubble layer in femtosecond laser-assisted LASIK: a novel technique
description	A John Kanellopoulos,1,2 George Asimellis11Laservision Eye Institute, Athens, Greece; 2New York University School of Medicine, New York, NY, USABackground: The purpose of this study was to determine flap parameter accuracy, extent of the opaque bubble layer, and incidence of skip lines in femtosecond laser-assisted stromal in situ keratomileusis (LASIK) using the WaveLight&reg; FS200 laser and optoelectronic clinical measurements.Methods: Images from 101 flaps were automatically recorded during consecutive routine LASIK procedures performed using the WaveLight FS200 femtosecond laser and the EX500 excimer laser. Digital processing of these images was used to evaluate objectively the diameter of FS200-created flaps, by comparing planned versus achieved procedures and to evaluate the incidence and extent (area) of the opaque bubble layer.Results: The intended flap diameters were between 8.00 mm and 9.50 mm. The achieved flap diameters showed extremely high precision, and were on average -0.16 &plusmn; 0.04 mm smaller for a 8.00 mm intended flap diameter, -0.12 &plusmn; 0.03 mm smaller for a 8.50 mm flap, and up +0.06 &plusmn; 0.06 mm wider for a 9.50 mm flap. With an average flap area of 72.4 mm2, the mean area of the opaque bubble layer (4.1 &plusmn; 4.3 [range 0&ndash;14.34] mm2) corresponded to a 6% opaque bubble layer-to-flap area. Specifically, 80% of the femtosecond-created flaps had an essentially zero opaque bubble layer (&lt;2.7% of the flap area).Conclusion: In our clinical experience, flaps created using FS200 and this novel highly objective assessment technique demonstrate both precision and reproducibility. The incidence of opaque bubble layer was minimal.Keywords: femtosecond laser precision, bladeless laser-assisted stromal in situ keratomileusis, corneal flap diameter, opaque bubble layer, skip lines, WaveLight FS200
format	article
author	Kanellopoulos AJ Asimellis G
author_facet	Kanellopoulos AJ Asimellis G
author_sort	Kanellopoulos AJ
title	Digital analysis of flap parameter accuracy and objective assessment of opaque bubble layer in femtosecond laser-assisted LASIK: a novel technique
title_short	Digital analysis of flap parameter accuracy and objective assessment of opaque bubble layer in femtosecond laser-assisted LASIK: a novel technique
title_full	Digital analysis of flap parameter accuracy and objective assessment of opaque bubble layer in femtosecond laser-assisted LASIK: a novel technique
title_fullStr	Digital analysis of flap parameter accuracy and objective assessment of opaque bubble layer in femtosecond laser-assisted LASIK: a novel technique
title_full_unstemmed	Digital analysis of flap parameter accuracy and objective assessment of opaque bubble layer in femtosecond laser-assisted LASIK: a novel technique
title_sort	digital analysis of flap parameter accuracy and objective assessment of opaque bubble layer in femtosecond laser-assisted lasik: a novel technique
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/b6bd35c2d49f49ca832fa7491e87c10c
work_keys_str_mv	AT kanellopoulosaj digitalanalysisofflapparameteraccuracyandobjectiveassessmentofopaquebubblelayerinfemtosecondlaserassistedlasikanoveltechnique AT asimellisg digitalanalysisofflapparameteraccuracyandobjectiveassessmentofopaquebubblelayerinfemtosecondlaserassistedlasikanoveltechnique
_version_	1718402371504046080

Digital analysis of flap parameter accuracy and objective assessment of opaque bubble layer in femtosecond laser-assisted LASIK: a novel technique

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