It Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis
A Migliore,1 G Gigliucci,1 RJ Petrella,2 RR Bannuru,3 X Chevalier,4 E Maheu,5 R Raman,6 G Herrero-Beaumont,7 N Isailovic,8 M Matucci Cerinc9 1Rheumatology Unit, San Pietro Fatebenefratelli Hospital, Rome, Italy; 2Department of Family Medicine, School of Kinesiology Western University, Western Centre...
Guardado en:
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Dove Medical Press
2019
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/b6cc9d70d96343b38c64778bd5961d24 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:b6cc9d70d96343b38c64778bd5961d24 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:b6cc9d70d96343b38c64778bd5961d242021-12-02T11:11:57ZIt Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis1178-203Xhttps://doaj.org/article/b6cc9d70d96343b38c64778bd5961d242019-12-01T00:00:00Zhttps://www.dovepress.com/it-is-the-time-to-think-about-a-treat-to-target-strategy-for-knee-oste-peer-reviewed-article-TCRMhttps://doaj.org/toc/1178-203XA Migliore,1 G Gigliucci,1 RJ Petrella,2 RR Bannuru,3 X Chevalier,4 E Maheu,5 R Raman,6 G Herrero-Beaumont,7 N Isailovic,8 M Matucci Cerinc9 1Rheumatology Unit, San Pietro Fatebenefratelli Hospital, Rome, Italy; 2Department of Family Medicine, School of Kinesiology Western University, Western Centre for Public Health & Family, London, Ontario, Canada; 3Center for Treatment Comparison and Integrative Analysis Division of Rheumatology, Tufts Medical Center, Boston, MA, USA; 4Department of Rheumatology, Hôpital Henri Mondor, Creteil, France; 5Rheumatology Department, AP-HP, Saint-Antoine Hospital, Paris, France; 6Academic Department of Orthopaedics, Hull and East Yorkshire NHS Trust, Castle Hill Hospital, Cottingham, UK; 7Joint and Bone Research Unit, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain; 8Division of Rheumatology and Clinical Immunology, Humanitas Research Hospital, Rozzano, Milan, Italy; 9Division of Rheumatology AOUC, Department of Experimental and Clinical Medicine, University of Florence, Florence, ItalyCorrespondence: N IsailovicDivision of Rheumatology and Clinical Immunology, Humanitas Research Hospital, Via A. Manzoni 56, Rozzano 20089, Milan, ItalyTel +39-02-8224-5118Email natasa.isailovic@humanitasresearch.itAbstract: Osteoarthritis (OA) is a rheumatic disease that affects the well-being of the patient, compromises physical and mental function, and affects other quality of life aspects. In the literature, several evidence-based guidelines and recommendations for the management of knee osteoarthritis (KOA) are available. These recommendations list the different therapeutic options rather than addressing a hierarchy between the treatments and defining the real target. Therefore, a question arises: are patients and physicians satisfied with the current management of KOA? Actually, the answer may be negative, thus suggesting a change in our therapeutic strategies. In this article, we address this challenge by suggesting that it is time to develop a “treat to target strategy” for KOA.Keywords: osteoarthritis, knee osteoarthritis, treat to targetMigliore AGigliucci GPetrella RJBannuru RRChevalier XMaheu ERaman RHerrero-Beaumont GIsailovic NMatucci Cerinc MDove Medical Pressarticleosteoarthritisknee osteoarthritistreat to targetTherapeutics. PharmacologyRM1-950ENTherapeutics and Clinical Risk Management, Vol Volume 15, Pp 1479-1482 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
osteoarthritis knee osteoarthritis treat to target Therapeutics. Pharmacology RM1-950 |
| spellingShingle |
osteoarthritis knee osteoarthritis treat to target Therapeutics. Pharmacology RM1-950 Migliore A Gigliucci G Petrella RJ Bannuru RR Chevalier X Maheu E Raman R Herrero-Beaumont G Isailovic N Matucci Cerinc M It Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis |
| description |
A Migliore,1 G Gigliucci,1 RJ Petrella,2 RR Bannuru,3 X Chevalier,4 E Maheu,5 R Raman,6 G Herrero-Beaumont,7 N Isailovic,8 M Matucci Cerinc9 1Rheumatology Unit, San Pietro Fatebenefratelli Hospital, Rome, Italy; 2Department of Family Medicine, School of Kinesiology Western University, Western Centre for Public Health & Family, London, Ontario, Canada; 3Center for Treatment Comparison and Integrative Analysis Division of Rheumatology, Tufts Medical Center, Boston, MA, USA; 4Department of Rheumatology, Hôpital Henri Mondor, Creteil, France; 5Rheumatology Department, AP-HP, Saint-Antoine Hospital, Paris, France; 6Academic Department of Orthopaedics, Hull and East Yorkshire NHS Trust, Castle Hill Hospital, Cottingham, UK; 7Joint and Bone Research Unit, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain; 8Division of Rheumatology and Clinical Immunology, Humanitas Research Hospital, Rozzano, Milan, Italy; 9Division of Rheumatology AOUC, Department of Experimental and Clinical Medicine, University of Florence, Florence, ItalyCorrespondence: N IsailovicDivision of Rheumatology and Clinical Immunology, Humanitas Research Hospital, Via A. Manzoni 56, Rozzano 20089, Milan, ItalyTel +39-02-8224-5118Email natasa.isailovic@humanitasresearch.itAbstract: Osteoarthritis (OA) is a rheumatic disease that affects the well-being of the patient, compromises physical and mental function, and affects other quality of life aspects. In the literature, several evidence-based guidelines and recommendations for the management of knee osteoarthritis (KOA) are available. These recommendations list the different therapeutic options rather than addressing a hierarchy between the treatments and defining the real target. Therefore, a question arises: are patients and physicians satisfied with the current management of KOA? Actually, the answer may be negative, thus suggesting a change in our therapeutic strategies. In this article, we address this challenge by suggesting that it is time to develop a “treat to target strategy” for KOA.Keywords: osteoarthritis, knee osteoarthritis, treat to target |
| format |
article |
| author |
Migliore A Gigliucci G Petrella RJ Bannuru RR Chevalier X Maheu E Raman R Herrero-Beaumont G Isailovic N Matucci Cerinc M |
| author_facet |
Migliore A Gigliucci G Petrella RJ Bannuru RR Chevalier X Maheu E Raman R Herrero-Beaumont G Isailovic N Matucci Cerinc M |
| author_sort |
Migliore A |
| title |
It Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis |
| title_short |
It Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis |
| title_full |
It Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis |
| title_fullStr |
It Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis |
| title_full_unstemmed |
It Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis |
| title_sort |
it is the time to think about a treat-to-target strategy for knee osteoarthritis |
| publisher |
Dove Medical Press |
| publishDate |
2019 |
| url |
https://doaj.org/article/b6cc9d70d96343b38c64778bd5961d24 |
| work_keys_str_mv |
AT migliorea itisthetimetothinkaboutatreattotargetstrategyforkneeosteoarthritis AT gigliuccig itisthetimetothinkaboutatreattotargetstrategyforkneeosteoarthritis AT petrellarj itisthetimetothinkaboutatreattotargetstrategyforkneeosteoarthritis AT bannururr itisthetimetothinkaboutatreattotargetstrategyforkneeosteoarthritis AT chevalierx itisthetimetothinkaboutatreattotargetstrategyforkneeosteoarthritis AT maheue itisthetimetothinkaboutatreattotargetstrategyforkneeosteoarthritis AT ramanr itisthetimetothinkaboutatreattotargetstrategyforkneeosteoarthritis AT herrerobeaumontg itisthetimetothinkaboutatreattotargetstrategyforkneeosteoarthritis AT isailovicn itisthetimetothinkaboutatreattotargetstrategyforkneeosteoarthritis AT matuccicerincm itisthetimetothinkaboutatreattotargetstrategyforkneeosteoarthritis |
| _version_ |
1718396183670423552 |