DREAM: a database of experimentally supported protein-coding RNAs and drug associations in human cancer

Abstract The Drug Response Gene Expression Associated Map, also referred as “DREAM” ( http://bio-big-data.cn:8080/DREAM ), is a manually curated database of experimentally supported protein-coding RNAs and drugs associations in human cancers. The current version of the DREAM documents 3048 entries a...

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Autores principales:	Shupeng Li, Lulu Li, Xiangqi Meng, Penggang Sun, Yi Liu, Yuntang Song, Sijia Zhang, Chuanlu Jiang, Jinquan Cai, Zheng Zhao
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Drugs Human cancers Database Data visualization Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/b6cccfdf19e44a059039749aef86971a
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spelling	oai:doaj.org-article:b6cccfdf19e44a059039749aef86971a2021-11-14T12:05:33ZDREAM: a database of experimentally supported protein-coding RNAs and drug associations in human cancer10.1186/s12943-021-01436-11476-4598https://doaj.org/article/b6cccfdf19e44a059039749aef86971a2021-11-01T00:00:00Zhttps://doi.org/10.1186/s12943-021-01436-1https://doaj.org/toc/1476-4598Abstract The Drug Response Gene Expression Associated Map, also referred as “DREAM” ( http://bio-big-data.cn:8080/DREAM ), is a manually curated database of experimentally supported protein-coding RNAs and drugs associations in human cancers. The current version of the DREAM documents 3048 entries about scientific literatures supported drug sensitivity or drug intervention related protein-coding RNAs from PubMed database and 195 high-throughput microarray data about drug sensitivity or drug intervention related protein-coding RNAs data from GEO database. Each entry in DREAM database contains detailed information on protein-coding RNA, drug, cancer, and other information including title, PubMed ID, journal, publish time. The DREAM database also provides some data visualization and online analysis services such as volcano plot, GO/KEGG enrichment function analysis, and novel drug discovery analysis. We hope the DREAM database should serve as a valuable resource for clinical practice and basic research, which could help researchers better understand the effects of protein-coding RNAs on drug response in human cancers.Shupeng LiLulu LiXiangqi MengPenggang SunYi LiuYuntang SongSijia ZhangChuanlu JiangJinquan CaiZheng ZhaoBMCarticleDrugsHuman cancersDatabaseData visualizationNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENMolecular Cancer, Vol 20, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Drugs Human cancers Database Data visualization Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Drugs Human cancers Database Data visualization Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Shupeng Li Lulu Li Xiangqi Meng Penggang Sun Yi Liu Yuntang Song Sijia Zhang Chuanlu Jiang Jinquan Cai Zheng Zhao DREAM: a database of experimentally supported protein-coding RNAs and drug associations in human cancer
description	Abstract The Drug Response Gene Expression Associated Map, also referred as “DREAM” ( http://bio-big-data.cn:8080/DREAM ), is a manually curated database of experimentally supported protein-coding RNAs and drugs associations in human cancers. The current version of the DREAM documents 3048 entries about scientific literatures supported drug sensitivity or drug intervention related protein-coding RNAs from PubMed database and 195 high-throughput microarray data about drug sensitivity or drug intervention related protein-coding RNAs data from GEO database. Each entry in DREAM database contains detailed information on protein-coding RNA, drug, cancer, and other information including title, PubMed ID, journal, publish time. The DREAM database also provides some data visualization and online analysis services such as volcano plot, GO/KEGG enrichment function analysis, and novel drug discovery analysis. We hope the DREAM database should serve as a valuable resource for clinical practice and basic research, which could help researchers better understand the effects of protein-coding RNAs on drug response in human cancers.
format	article
author	Shupeng Li Lulu Li Xiangqi Meng Penggang Sun Yi Liu Yuntang Song Sijia Zhang Chuanlu Jiang Jinquan Cai Zheng Zhao
author_facet	Shupeng Li Lulu Li Xiangqi Meng Penggang Sun Yi Liu Yuntang Song Sijia Zhang Chuanlu Jiang Jinquan Cai Zheng Zhao
author_sort	Shupeng Li
title	DREAM: a database of experimentally supported protein-coding RNAs and drug associations in human cancer
title_short	DREAM: a database of experimentally supported protein-coding RNAs and drug associations in human cancer
title_full	DREAM: a database of experimentally supported protein-coding RNAs and drug associations in human cancer
title_fullStr	DREAM: a database of experimentally supported protein-coding RNAs and drug associations in human cancer
title_full_unstemmed	DREAM: a database of experimentally supported protein-coding RNAs and drug associations in human cancer
title_sort	dream: a database of experimentally supported protein-coding rnas and drug associations in human cancer
publisher	BMC
publishDate	2021
url	https://doaj.org/article/b6cccfdf19e44a059039749aef86971a
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DREAM: a database of experimentally supported protein-coding RNAs and drug associations in human cancer

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