A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins.
Kaposi sarcoma-associated herpesvirus (KSHV) establishes a lifelong latent infection and causes several malignancies in humans. Murine herpesvirus 68 (MHV-68) is a related γ2-herpesvirus frequently used as a model to study the biology of γ-herpesviruses in vivo. The KSHV latency-associated nuclear a...
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Auteurs principaux: | Jan Hellert, Magdalena Weidner-Glunde, Joern Krausze, Ulrike Richter, Heiko Adler, Roman Fedorov, Marcel Pietrek, Jessica Rückert, Christiane Ritter, Thomas F Schulz, Thorsten Lührs |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Sujets: | |
Accès en ligne: | https://doaj.org/article/b6ce63ee0f1f4a07b014395c34b3a3d9 |
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