Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis

Ramses Gallegos-Monterrosa, Mathilde Nordgaard Christensen, and colleagues investigate how a single or double deletion of the rap-phr genes, parts of peptide-based quorum sensing systems, impacts the sporulation and biofilm formation of B. subtilis under four different conditions and a multitude of...

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Autores principales:	Ramses Gallegos-Monterrosa, Mathilde Nordgaard Christensen, Tino Barchewitz, Sonja Koppenhöfer, B. Priyadarshini, Balázs Bálint, Gergely Maróti, Paul J. Kempen, Anna Dragoš, Ákos T. Kovács
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/b6d4495effed4defa767a6e7cf523350
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spelling	oai:doaj.org-article:b6d4495effed4defa767a6e7cf5233502021-12-02T14:30:33ZImpact of Rap-Phr system abundance on adaptation of Bacillus subtilis10.1038/s42003-021-01983-92399-3642https://doaj.org/article/b6d4495effed4defa767a6e7cf5233502021-04-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01983-9https://doaj.org/toc/2399-3642Ramses Gallegos-Monterrosa, Mathilde Nordgaard Christensen, and colleagues investigate how a single or double deletion of the rap-phr genes, parts of peptide-based quorum sensing systems, impacts the sporulation and biofilm formation of B. subtilis under four different conditions and a multitude of strains. Using strain-specific barcoding and complete genome sequencing, the authors show that competitive selection is driven by acquired mutations, and that selected strains demonstrate increased spore fitness relative to their ancestors and wild types.Ramses Gallegos-MonterrosaMathilde Nordgaard ChristensenTino BarchewitzSonja KoppenhöferB. PriyadarshiniBalázs BálintGergely MarótiPaul J. KempenAnna DragošÁkos T. KovácsNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Ramses Gallegos-Monterrosa Mathilde Nordgaard Christensen Tino Barchewitz Sonja Koppenhöfer B. Priyadarshini Balázs Bálint Gergely Maróti Paul J. Kempen Anna Dragoš Ákos T. Kovács Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis
description	Ramses Gallegos-Monterrosa, Mathilde Nordgaard Christensen, and colleagues investigate how a single or double deletion of the rap-phr genes, parts of peptide-based quorum sensing systems, impacts the sporulation and biofilm formation of B. subtilis under four different conditions and a multitude of strains. Using strain-specific barcoding and complete genome sequencing, the authors show that competitive selection is driven by acquired mutations, and that selected strains demonstrate increased spore fitness relative to their ancestors and wild types.
format	article
author	Ramses Gallegos-Monterrosa Mathilde Nordgaard Christensen Tino Barchewitz Sonja Koppenhöfer B. Priyadarshini Balázs Bálint Gergely Maróti Paul J. Kempen Anna Dragoš Ákos T. Kovács
author_facet	Ramses Gallegos-Monterrosa Mathilde Nordgaard Christensen Tino Barchewitz Sonja Koppenhöfer B. Priyadarshini Balázs Bálint Gergely Maróti Paul J. Kempen Anna Dragoš Ákos T. Kovács
author_sort	Ramses Gallegos-Monterrosa
title	Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis
title_short	Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis
title_full	Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis
title_fullStr	Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis
title_full_unstemmed	Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis
title_sort	impact of rap-phr system abundance on adaptation of bacillus subtilis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b6d4495effed4defa767a6e7cf523350
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Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis

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