Interaction between genetic predisposition, smoking, and dementia risk: a population-based cohort study

Código QR

Interaction between genetic predisposition, smoking, and dementia risk: a population-based cohort study

Abstract We evaluated whether the association between cigarette smoking and dementia risk is modified by genetic predisposition including apolipoprotein E (APOE) genotype and polygenic risk (excluding the APOE region). We included 193,198 UK Biobank participants aged 60–73 years without dementia at...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Na Zhang, Janice M. Ranson, Zhi-Jie Zheng, Eilis Hannon, Zhenwei Zhou, Xuejun Kong, David J. Llewellyn, Daniel A. King, Jie Huang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b6daf5cefaee4cfdb8f7143e65149d47
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Genetic predisposition to tinnitus in the UK Biobank population
por: Madeleine E. Urbanek, et al.
Publicado: (2021)

Genetic predispositions moderate the effectiveness of tobacco excise taxes.
por: Eric A W Slob, et al.
Publicado: (2021)

Should All Individuals Be Screened for Genetic Predisposition to Cancer?
por: Sarah Wedderburn, et al.
Publicado: (2021)

Search for genetic markers of predisposition to psoriasis and psoriatic arthritis
por: M. V. Smolnikova, et al.
Publicado: (2020)

Genetic predispositions moderate the effectiveness of tobacco excise taxes
por: Eric A. W. Slob, et al.
Publicado: (2021)

Investigating the role of mitochondrial haplogroups in genetic predisposition to meningococcal disease.
por: Antonio Salas, et al.
Publicado: (2009)

Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women
por: Valgerdur Steinthorsdottir, et al.
Publicado: (2020)

Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics
por: Helen E. Speedy, et al.
Publicado: (2019)

The role of genetics in neurodegenerative dementia: a large cohort study in South China
por: Bin Jiao, et al.
Publicado: (2021)

Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition
por: Nadav Brandes, et al.
Publicado: (2021)

Analysis of the genetic predisposition to develop a Myocardial Infarction in a sample of Moroccan patients
por: Anaibar Fatima Ezzahra, et al.
Publicado: (2021)

Model Identifies Genetic Predisposition of Alzheimer’s Disease as Key Decider in Cell Susceptibility to Stress
por: Ioanna C. Stefani, et al.
Publicado: (2021)

Influence of depression on genetic predisposition to type 2 diabetes in a multiethnic longitudinal study
por: Sophiya Garasia, et al.
Publicado: (2017)

Inherited predisposition to breast cancer in the Carolina Breast Cancer Study
por: Tom Walsh, et al.
Publicado: (2021)

Polymorphic variants of glutathione reductase – new genetic markers of predisposition to type 2 diabetes mellitus
por: Iuliia E. Azarova, et al.
Publicado: (2021)

Interaction of caregiver-expressed emotions and neuropsychiatric symptoms in persons with dementia: a longitudinal cohort study
por: Kay Deckers, et al.
Publicado: (2021)

An alternative model for (breast) cancer predisposition
por: Erik Teugels, et al.
Publicado: (2017)

Editorial: The Skin in Cancer Predisposition Syndromes
por: Licia Turolla, et al.
Publicado: (2021)

Passive smoking and risk of type 2 diabetes: a meta-analysis of prospective cohort studies.
por: Ying Wang, et al.
Publicado: (2013)

Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies
por: Junjun Wang, et al.
Publicado: (2017)

Genetic Predisposition To Acquire a Polybasic Cleavage Site for Highly Pathogenic Avian Influenza Virus Hemagglutinin
por: Naganori Nao, et al.
Publicado: (2017)

Disorder predispositions and protections of Labrador Retrievers in the UK
por: Camilla Pegram, et al.
Publicado: (2021)

ASSOCIATION OF IL-1β, IL-4 AND IL-6 GENES POLYMORPHISMS WITH GENETIC PREDISPOSITION FOR AUTOIMMUNE THYROIDITIS
por: E. M. Biktagirova, et al.
Publicado: (2014)

Relevance of the dietary glycemic index, glycemic load and genetic predisposition for the glucose homeostasis of Chinese adults without diabetes
por: Guo Cheng, et al.
Publicado: (2017)

Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis.
por: Petroula Proitsi, et al.
Publicado: (2014)

Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: A cohort study in the UK Biobank.
por: Yuan Zhang, et al.
Publicado: (2021)

Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: A cohort study in the UK Biobank
por: Yuan Zhang, et al.
Publicado: (2021)

Genetic architecture of epigenetic and neuronal ageing rates in human brain regions
por: Ake T. Lu, et al.
Publicado: (2017)

Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.
por: Shengxu Li, et al.
Publicado: (2010)

Predictors of Current DSM-5 PTSD Diagnosis and Symptom Severity Among Deployed Veterans: Significance of Predisposition, Stress Exposure, and Genetics
por: Hu Y, et al.
Publicado: (2020)

Heterozygous APC germline mutations impart predisposition to colorectal cancer
por: Livia Preisler, et al.
Publicado: (2021)

Possible association between SIRT1 single nucleotide polymorphisms and predisposition to antisocial personality traits in Chinese adolescents
por: Hongjuan Chang, et al.
Publicado: (2017)

Effects of ApoE genotype on clinical phenotypes in early‐onset and late‐onset Alzheimer's disease in China: Data from the PUMCH dementia cohort
por: Liling Dong, et al.
Publicado: (2021)

Kidney disease and risk of dementia: a Danish nationwide cohort study
por: Henrik T Sørensen, et al.
Publicado: (2021)

Lung cancer risk in non-smoking females with a familial history of cancer: a multi-center prospective cohort study in China
por: Fei Wang, et al.
Publicado: (2021)

Genetic Analysis of Chinese Patients with Early-Onset Dementia Using Next-Generation Sequencing
por: Han LH, et al.
Publicado: (2020)

Identification of Genetic Predisposition in Noncirrhotic Portal Hypertension Patients With Multiple Renal Cysts by Integrated Analysis of Whole-Genome and Single-Cell RNA Sequencing
por: Yanjing Wu, et al.
Publicado: (2021)

Associations of hypertension burden on subsequent dementia: a population-based cohort study
por: Hyunjean Jung, et al.
Publicado: (2021)

The Effect of Sociodemographics, Physical Function, and Mood on Dementia Screening in a Multicultural Cohort
por: Tolea MI, et al.
Publicado: (2020)

Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum
por: Ake T. Lu, et al.
Publicado: (2016)