Crystal structure of the DNA-binding domain of Myelin-gene Regulatory Factor

Crystal structure of the DNA-binding domain of Myelin-gene Regulatory Factor

Abstract Myelin-gene Regulatory Factor (MyRF) is one of the master transcription factors controlling myelin formation and development in oligodendrocytes which is crucial for the powerful brain functions. The N-terminal of MyRF, which contains a proline-rich region and a DNA binding domain (DBD), is...

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Autores principales: Xiangkai Zhen, Bowen Li, Fen Hu, Shufeng Yan, Gabriele Meloni, Huiliang Li, Ning Shi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/b6e4e83ed74743899d7bf5d8ab1f5acf
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