Iterative protecting group-free cross-coupling leading to chiral multiply arylated structures
The Suzuki-Miyaura cross coupling is widely used in industrial and academic settings for the formation of carbon-carbon bonds. Here, the authors report a procedure whereby a molecule with multiple reactive carbon-boron bonds can undergo sequential, selective Suzuki-Miyaura reactions without the need...
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Nature Portfolio
2016
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oai:doaj.org-article:b6e9f665794b4f5382ac5381ac70e9eb2021-12-02T15:34:59ZIterative protecting group-free cross-coupling leading to chiral multiply arylated structures10.1038/ncomms110652041-1723https://doaj.org/article/b6e9f665794b4f5382ac5381ac70e9eb2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11065https://doaj.org/toc/2041-1723The Suzuki-Miyaura cross coupling is widely used in industrial and academic settings for the formation of carbon-carbon bonds. Here, the authors report a procedure whereby a molecule with multiple reactive carbon-boron bonds can undergo sequential, selective Suzuki-Miyaura reactions without the need for protecting groups.Cathleen M. CruddenChristopher ZiebenhausJason P. G. RygusKazem GhozatiPhillip J. UnsworthMasakazu NamboSamantha VothMarieke HutchinsonVeronique S. LabergeYuuki MaekawaDaisuke ImaoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016) |
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Science Q |
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Science Q Cathleen M. Crudden Christopher Ziebenhaus Jason P. G. Rygus Kazem Ghozati Phillip J. Unsworth Masakazu Nambo Samantha Voth Marieke Hutchinson Veronique S. Laberge Yuuki Maekawa Daisuke Imao Iterative protecting group-free cross-coupling leading to chiral multiply arylated structures |
description |
The Suzuki-Miyaura cross coupling is widely used in industrial and academic settings for the formation of carbon-carbon bonds. Here, the authors report a procedure whereby a molecule with multiple reactive carbon-boron bonds can undergo sequential, selective Suzuki-Miyaura reactions without the need for protecting groups. |
format |
article |
author |
Cathleen M. Crudden Christopher Ziebenhaus Jason P. G. Rygus Kazem Ghozati Phillip J. Unsworth Masakazu Nambo Samantha Voth Marieke Hutchinson Veronique S. Laberge Yuuki Maekawa Daisuke Imao |
author_facet |
Cathleen M. Crudden Christopher Ziebenhaus Jason P. G. Rygus Kazem Ghozati Phillip J. Unsworth Masakazu Nambo Samantha Voth Marieke Hutchinson Veronique S. Laberge Yuuki Maekawa Daisuke Imao |
author_sort |
Cathleen M. Crudden |
title |
Iterative protecting group-free cross-coupling leading to chiral multiply arylated structures |
title_short |
Iterative protecting group-free cross-coupling leading to chiral multiply arylated structures |
title_full |
Iterative protecting group-free cross-coupling leading to chiral multiply arylated structures |
title_fullStr |
Iterative protecting group-free cross-coupling leading to chiral multiply arylated structures |
title_full_unstemmed |
Iterative protecting group-free cross-coupling leading to chiral multiply arylated structures |
title_sort |
iterative protecting group-free cross-coupling leading to chiral multiply arylated structures |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/b6e9f665794b4f5382ac5381ac70e9eb |
work_keys_str_mv |
AT cathleenmcrudden iterativeprotectinggroupfreecrosscouplingleadingtochiralmultiplyarylatedstructures AT christopherziebenhaus iterativeprotectinggroupfreecrosscouplingleadingtochiralmultiplyarylatedstructures AT jasonpgrygus iterativeprotectinggroupfreecrosscouplingleadingtochiralmultiplyarylatedstructures AT kazemghozati iterativeprotectinggroupfreecrosscouplingleadingtochiralmultiplyarylatedstructures AT phillipjunsworth iterativeprotectinggroupfreecrosscouplingleadingtochiralmultiplyarylatedstructures AT masakazunambo iterativeprotectinggroupfreecrosscouplingleadingtochiralmultiplyarylatedstructures AT samanthavoth iterativeprotectinggroupfreecrosscouplingleadingtochiralmultiplyarylatedstructures AT mariekehutchinson iterativeprotectinggroupfreecrosscouplingleadingtochiralmultiplyarylatedstructures AT veroniqueslaberge iterativeprotectinggroupfreecrosscouplingleadingtochiralmultiplyarylatedstructures AT yuukimaekawa iterativeprotectinggroupfreecrosscouplingleadingtochiralmultiplyarylatedstructures AT daisukeimao iterativeprotectinggroupfreecrosscouplingleadingtochiralmultiplyarylatedstructures |
_version_ |
1718386677517385728 |