Induction ovulation with use of low dose HMG in patients with Clomiphene Citrate resistant polycystic ovary syndrome (PCOs)

Background and Objective: The aim of this study was to assess the follicular response in induction of ovulation with the of low dose human menopausal gonadotropin (HMG) in patients with clomiphene citrate resistant PCOs. Methods: This semi-experimental study was performed on 12 patients with clomiph...

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Autores principales: T Nazari, M Zeinal Zadeh, S Esmaeil Zadeh
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Publicado: Babol University of Medical Sciences 2003
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spelling oai:doaj.org-article:b6eec95c051041ecb2f804f2b33c98a52021-11-10T09:18:07ZInduction ovulation with use of low dose HMG in patients with Clomiphene Citrate resistant polycystic ovary syndrome (PCOs)1561-41072251-7170https://doaj.org/article/b6eec95c051041ecb2f804f2b33c98a52003-04-01T00:00:00Zhttp://jbums.org/article-1-2768-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: The aim of this study was to assess the follicular response in induction of ovulation with the of low dose human menopausal gonadotropin (HMG) in patients with clomiphene citrate resistant PCOs. Methods: This semi-experimental study was performed on 12 patients with clomiphene citrate resistant PCOs in Fatemeh Zahra infertility center. Induction ovulation was started with 37.5 (IU) of HMG daily and then was increased by 75IU according to follicular response. Patients were exactly monitored by vaginal sonography. Findings: Eight patients showed suitable follicular response to induction, of whom 2 conceived. In 4 patients, their cycles had cancelled because no follicular response was observed in spite of increasing dose to 75IU until midcycle. Ovarian hyperstimulation syndrome (OHSS) was not observed in any of them. Conclusion: Administration of low dose HMG can be used successfully to stimulate follicular growth in patients with clomiphene citrate resistant PCOs.T NazariM Zeinal ZadehS Esmaeil ZadehBabol University of Medical Sciencesarticleinduction ovulationpolycystic ovarian syndrome (pcos)human menopausal gonadotropin (hmg)MedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 5, Iss 2, Pp 19-23 (2003)
institution DOAJ
collection DOAJ
language EN
FA
topic induction ovulation
polycystic ovarian syndrome (pcos)
human menopausal gonadotropin (hmg)
Medicine
R
Medicine (General)
R5-920
spellingShingle induction ovulation
polycystic ovarian syndrome (pcos)
human menopausal gonadotropin (hmg)
Medicine
R
Medicine (General)
R5-920
T Nazari
M Zeinal Zadeh
S Esmaeil Zadeh
Induction ovulation with use of low dose HMG in patients with Clomiphene Citrate resistant polycystic ovary syndrome (PCOs)
description Background and Objective: The aim of this study was to assess the follicular response in induction of ovulation with the of low dose human menopausal gonadotropin (HMG) in patients with clomiphene citrate resistant PCOs. Methods: This semi-experimental study was performed on 12 patients with clomiphene citrate resistant PCOs in Fatemeh Zahra infertility center. Induction ovulation was started with 37.5 (IU) of HMG daily and then was increased by 75IU according to follicular response. Patients were exactly monitored by vaginal sonography. Findings: Eight patients showed suitable follicular response to induction, of whom 2 conceived. In 4 patients, their cycles had cancelled because no follicular response was observed in spite of increasing dose to 75IU until midcycle. Ovarian hyperstimulation syndrome (OHSS) was not observed in any of them. Conclusion: Administration of low dose HMG can be used successfully to stimulate follicular growth in patients with clomiphene citrate resistant PCOs.
format article
author T Nazari
M Zeinal Zadeh
S Esmaeil Zadeh
author_facet T Nazari
M Zeinal Zadeh
S Esmaeil Zadeh
author_sort T Nazari
title Induction ovulation with use of low dose HMG in patients with Clomiphene Citrate resistant polycystic ovary syndrome (PCOs)
title_short Induction ovulation with use of low dose HMG in patients with Clomiphene Citrate resistant polycystic ovary syndrome (PCOs)
title_full Induction ovulation with use of low dose HMG in patients with Clomiphene Citrate resistant polycystic ovary syndrome (PCOs)
title_fullStr Induction ovulation with use of low dose HMG in patients with Clomiphene Citrate resistant polycystic ovary syndrome (PCOs)
title_full_unstemmed Induction ovulation with use of low dose HMG in patients with Clomiphene Citrate resistant polycystic ovary syndrome (PCOs)
title_sort induction ovulation with use of low dose hmg in patients with clomiphene citrate resistant polycystic ovary syndrome (pcos)
publisher Babol University of Medical Sciences
publishDate 2003
url https://doaj.org/article/b6eec95c051041ecb2f804f2b33c98a5
work_keys_str_mv AT tnazari inductionovulationwithuseoflowdosehmginpatientswithclomiphenecitrateresistantpolycysticovarysyndromepcos
AT mzeinalzadeh inductionovulationwithuseoflowdosehmginpatientswithclomiphenecitrateresistantpolycysticovarysyndromepcos
AT sesmaeilzadeh inductionovulationwithuseoflowdosehmginpatientswithclomiphenecitrateresistantpolycysticovarysyndromepcos
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