Should we vaccinate the better seroconverters or the most vulnerable? Game changing insights for COVID-19 vaccine prioritization policies
Abstract Background With the rapid rise in COVID 19 cases incomparable to the number of vaccinations available, there has been a demand to prioritize the older age groups receiving the vaccine as they have more risk of morbidity and mortality and thus better outcome from vaccination. Main body Some...
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oai:doaj.org-article:b6f12f9028774024ba2ddac424d083262021-12-05T12:24:21ZShould we vaccinate the better seroconverters or the most vulnerable? Game changing insights for COVID-19 vaccine prioritization policies10.1186/s43054-021-00086-82090-9942https://doaj.org/article/b6f12f9028774024ba2ddac424d083262021-12-01T00:00:00Zhttps://doi.org/10.1186/s43054-021-00086-8https://doaj.org/toc/2090-9942Abstract Background With the rapid rise in COVID 19 cases incomparable to the number of vaccinations available, there has been a demand to prioritize the older age groups receiving the vaccine as they have more risk of morbidity and mortality and thus better outcome from vaccination. Main body Some studies showed a lower seroconversion rate in older group patients; thus, we discuss the necessity to reprioritize vaccinations to younger age groups who have better seroconversion rates, but we may face some ethical dilemma that could hinder our hypothesis. Decreased seroconversion rates in adults are attributable to immuno-senescence which involves a decrease in humoral and cellular-mediated immunity with age. Despite this fact, there remains some ethical dilemma that can hinder widespread vaccination of younger generations, the most important of which is the unknown long-term effects of COVID-19 vaccines due their fast-tracking under the pressure of the pandemic. Short conclusion Prioritizing children vaccination against COVID-19 seems an interesting strategy that can help in containing the pandemic. Resolving some ethical dilemma needs to be done before implementing such strategy.Antoine AbdelMassihMeryam El ShershabyHanya GaberMenna HabibNada GamalReem HusseinyNada AlShehryAbeer AminBassant HeikalNadine El-HusseinyMai MoursiHabiba-Allah IsmailSara SenoussyReem ElSharkawyHebat Allah AlZayatGhada ElMahdyHossameldin MoawadAli GenenaAhmed ElKikiMary RedaMohamed KhalilReem Al RamadyNoran RadwanMariam Khaled-Ibn-ElWalidHager AminRafeef HozaienAya KamelRaghda FoudaSpringerOpenarticleSeroconversionCOVID-19 vaccinesPrioritization policyPediatricsRJ1-570ENEgyptian Pediatric Association Gazette, Vol 69, Iss 1, Pp 1-8 (2021) |
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Seroconversion COVID-19 vaccines Prioritization policy Pediatrics RJ1-570 |
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Seroconversion COVID-19 vaccines Prioritization policy Pediatrics RJ1-570 Antoine AbdelMassih Meryam El Shershaby Hanya Gaber Menna Habib Nada Gamal Reem Husseiny Nada AlShehry Abeer Amin Bassant Heikal Nadine El-Husseiny Mai Moursi Habiba-Allah Ismail Sara Senoussy Reem ElSharkawy Hebat Allah AlZayat Ghada ElMahdy Hossameldin Moawad Ali Genena Ahmed ElKiki Mary Reda Mohamed Khalil Reem Al Ramady Noran Radwan Mariam Khaled-Ibn-ElWalid Hager Amin Rafeef Hozaien Aya Kamel Raghda Fouda Should we vaccinate the better seroconverters or the most vulnerable? Game changing insights for COVID-19 vaccine prioritization policies |
| description |
Abstract Background With the rapid rise in COVID 19 cases incomparable to the number of vaccinations available, there has been a demand to prioritize the older age groups receiving the vaccine as they have more risk of morbidity and mortality and thus better outcome from vaccination. Main body Some studies showed a lower seroconversion rate in older group patients; thus, we discuss the necessity to reprioritize vaccinations to younger age groups who have better seroconversion rates, but we may face some ethical dilemma that could hinder our hypothesis. Decreased seroconversion rates in adults are attributable to immuno-senescence which involves a decrease in humoral and cellular-mediated immunity with age. Despite this fact, there remains some ethical dilemma that can hinder widespread vaccination of younger generations, the most important of which is the unknown long-term effects of COVID-19 vaccines due their fast-tracking under the pressure of the pandemic. Short conclusion Prioritizing children vaccination against COVID-19 seems an interesting strategy that can help in containing the pandemic. Resolving some ethical dilemma needs to be done before implementing such strategy. |
| format |
article |
| author |
Antoine AbdelMassih Meryam El Shershaby Hanya Gaber Menna Habib Nada Gamal Reem Husseiny Nada AlShehry Abeer Amin Bassant Heikal Nadine El-Husseiny Mai Moursi Habiba-Allah Ismail Sara Senoussy Reem ElSharkawy Hebat Allah AlZayat Ghada ElMahdy Hossameldin Moawad Ali Genena Ahmed ElKiki Mary Reda Mohamed Khalil Reem Al Ramady Noran Radwan Mariam Khaled-Ibn-ElWalid Hager Amin Rafeef Hozaien Aya Kamel Raghda Fouda |
| author_facet |
Antoine AbdelMassih Meryam El Shershaby Hanya Gaber Menna Habib Nada Gamal Reem Husseiny Nada AlShehry Abeer Amin Bassant Heikal Nadine El-Husseiny Mai Moursi Habiba-Allah Ismail Sara Senoussy Reem ElSharkawy Hebat Allah AlZayat Ghada ElMahdy Hossameldin Moawad Ali Genena Ahmed ElKiki Mary Reda Mohamed Khalil Reem Al Ramady Noran Radwan Mariam Khaled-Ibn-ElWalid Hager Amin Rafeef Hozaien Aya Kamel Raghda Fouda |
| author_sort |
Antoine AbdelMassih |
| title |
Should we vaccinate the better seroconverters or the most vulnerable? Game changing insights for COVID-19 vaccine prioritization policies |
| title_short |
Should we vaccinate the better seroconverters or the most vulnerable? Game changing insights for COVID-19 vaccine prioritization policies |
| title_full |
Should we vaccinate the better seroconverters or the most vulnerable? Game changing insights for COVID-19 vaccine prioritization policies |
| title_fullStr |
Should we vaccinate the better seroconverters or the most vulnerable? Game changing insights for COVID-19 vaccine prioritization policies |
| title_full_unstemmed |
Should we vaccinate the better seroconverters or the most vulnerable? Game changing insights for COVID-19 vaccine prioritization policies |
| title_sort |
should we vaccinate the better seroconverters or the most vulnerable? game changing insights for covid-19 vaccine prioritization policies |
| publisher |
SpringerOpen |
| publishDate |
2021 |
| url |
https://doaj.org/article/b6f12f9028774024ba2ddac424d08326 |
| work_keys_str_mv |
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