Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells

Yes-associated protein (YAP) is a growth-promoting transcription co-activator that regulates the malignancy of various cancers, however its regulation is not fully understood. Here the authors show that phosphatdylserine at recycling endosomes regulates YAP signalling pathway.

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Autores principales:	Tatsuyuki Matsudaira, Kojiro Mukai, Taishin Noguchi, Junya Hasegawa, Tomohisa Hatta, Shun-ichiro Iemura, Tohru Natsume, Norio Miyamura, Hiroshi Nishina, Jun Nakayama, Kentaro Semba, Takuya Tomita, Shigeo Murata, Hiroyuki Arai, Tomohiko Taguchi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b6f3cf39d78c4ceca7b038e194e9bed2
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spelling	oai:doaj.org-article:b6f3cf39d78c4ceca7b038e194e9bed22021-12-02T15:38:36ZEndosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells10.1038/s41467-017-01255-32041-1723https://doaj.org/article/b6f3cf39d78c4ceca7b038e194e9bed22017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01255-3https://doaj.org/toc/2041-1723Yes-associated protein (YAP) is a growth-promoting transcription co-activator that regulates the malignancy of various cancers, however its regulation is not fully understood. Here the authors show that phosphatdylserine at recycling endosomes regulates YAP signalling pathway.Tatsuyuki MatsudairaKojiro MukaiTaishin NoguchiJunya HasegawaTomohisa HattaShun-ichiro IemuraTohru NatsumeNorio MiyamuraHiroshi NishinaJun NakayamaKentaro SembaTakuya TomitaShigeo MurataHiroyuki AraiTomohiko TaguchiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tatsuyuki Matsudaira Kojiro Mukai Taishin Noguchi Junya Hasegawa Tomohisa Hatta Shun-ichiro Iemura Tohru Natsume Norio Miyamura Hiroshi Nishina Jun Nakayama Kentaro Semba Takuya Tomita Shigeo Murata Hiroyuki Arai Tomohiko Taguchi Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells
description	Yes-associated protein (YAP) is a growth-promoting transcription co-activator that regulates the malignancy of various cancers, however its regulation is not fully understood. Here the authors show that phosphatdylserine at recycling endosomes regulates YAP signalling pathway.
format	article
author	Tatsuyuki Matsudaira Kojiro Mukai Taishin Noguchi Junya Hasegawa Tomohisa Hatta Shun-ichiro Iemura Tohru Natsume Norio Miyamura Hiroshi Nishina Jun Nakayama Kentaro Semba Takuya Tomita Shigeo Murata Hiroyuki Arai Tomohiko Taguchi
author_facet	Tatsuyuki Matsudaira Kojiro Mukai Taishin Noguchi Junya Hasegawa Tomohisa Hatta Shun-ichiro Iemura Tohru Natsume Norio Miyamura Hiroshi Nishina Jun Nakayama Kentaro Semba Takuya Tomita Shigeo Murata Hiroyuki Arai Tomohiko Taguchi
author_sort	Tatsuyuki Matsudaira
title	Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells
title_short	Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells
title_full	Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells
title_fullStr	Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells
title_full_unstemmed	Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells
title_sort	endosomal phosphatidylserine is critical for the yap signalling pathway in proliferating cells
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/b6f3cf39d78c4ceca7b038e194e9bed2
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Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells

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