Possible algorithms for determining adverse reactions caused by food supplements in Romania

Introduction. The advertising of food supplements on various media channels or in specialty stores with natural products and other places, as well as the lack of informative and educational programs for the population upon side effects and the interaction of food supplements with food and drugs, hav...

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Autores principales:	Irina Mihaela MATRAN, Daniela Lucia MUNTEAN, Cristina NICULAS, Roxana Maria MARTIN-HADMAS, Monica TARCEA
Formato:	article
Lenguaje:	EN FR RO RU
Publicado:	Asociatia de Biosiguranta si Biosecuritate 2021
Materias:	nutrivigilence algorithms food supplements side effects. Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b6fc1e8d0dd14889be701322bd2c526d
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spelling	oai:doaj.org-article:b6fc1e8d0dd14889be701322bd2c526d2021-12-02T19:25:40ZPossible algorithms for determining adverse reactions caused by food supplements in Romania10.38045/ohrm.2021.4.012887-34582587-3466https://doaj.org/article/b6fc1e8d0dd14889be701322bd2c526d2021-10-01T00:00:00Zhttps://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/155/230https://doaj.org/toc/2887-3458https://doaj.org/toc/2587-3466Introduction. The advertising of food supplements on various media channels or in specialty stores with natural products and other places, as well as the lack of informative and educational programs for the population upon side effects and the interaction of food supplements with food and drugs, have led to the development of uncontrolled marketing of these products. Material and methods. PubMed, ResearchGate and EUR-Lex databases were analyzed during 2015-2021, based on search criteria based on: adverse reactions, ingredient new food, food supplements, algorithms. Results. Certain dietary supplements can cause multiple side effects, such as: impaired platelet function by decreased platelet aggregation, gastrointestinal side effects (diarrhea, vomiting), decreased wound healing/epithelialization, bacterial or fungal sepsis, most common in patients older. Herbal resources such as Aloe vera, Matricaria recutita, Taraxacum officinale and others, can cause dermatological side effects and inhibit the elimination of dermatological drugs metabolised by cytochrome P-450 (e.g. terbinafine). Matricaria recutita, Allium sativum, Mentha piperita L. and others, inhibit the enzyme CYP2C9. Another enzyme with a role in the metabolism of dermatological drugs and which is inhibited by plant resources is CYP3A4. Conclusions. It is imperative to legislate the reporting of adverse reactions caused by food supplements, including their interaction with food or drugs.Irina Mihaela MATRANDaniela Lucia MUNTEANCristina NICULASRoxana Maria MARTIN-HADMASMonica TARCEAAsociatia de Biosiguranta si Biosecuritatearticlenutrivigilencealgorithmsfood supplementsside effects.MedicineRScienceQENFRRORUOne Health & Risk Management, Vol 2, Iss 4, Pp 4-27 (2021)
institution	DOAJ
collection	DOAJ
language	EN FR RO RU
topic	nutrivigilence algorithms food supplements side effects. Medicine R Science Q
spellingShingle	nutrivigilence algorithms food supplements side effects. Medicine R Science Q Irina Mihaela MATRAN Daniela Lucia MUNTEAN Cristina NICULAS Roxana Maria MARTIN-HADMAS Monica TARCEA Possible algorithms for determining adverse reactions caused by food supplements in Romania
description	Introduction. The advertising of food supplements on various media channels or in specialty stores with natural products and other places, as well as the lack of informative and educational programs for the population upon side effects and the interaction of food supplements with food and drugs, have led to the development of uncontrolled marketing of these products. Material and methods. PubMed, ResearchGate and EUR-Lex databases were analyzed during 2015-2021, based on search criteria based on: adverse reactions, ingredient new food, food supplements, algorithms. Results. Certain dietary supplements can cause multiple side effects, such as: impaired platelet function by decreased platelet aggregation, gastrointestinal side effects (diarrhea, vomiting), decreased wound healing/epithelialization, bacterial or fungal sepsis, most common in patients older. Herbal resources such as Aloe vera, Matricaria recutita, Taraxacum officinale and others, can cause dermatological side effects and inhibit the elimination of dermatological drugs metabolised by cytochrome P-450 (e.g. terbinafine). Matricaria recutita, Allium sativum, Mentha piperita L. and others, inhibit the enzyme CYP2C9. Another enzyme with a role in the metabolism of dermatological drugs and which is inhibited by plant resources is CYP3A4. Conclusions. It is imperative to legislate the reporting of adverse reactions caused by food supplements, including their interaction with food or drugs.
format	article
author	Irina Mihaela MATRAN Daniela Lucia MUNTEAN Cristina NICULAS Roxana Maria MARTIN-HADMAS Monica TARCEA
author_facet	Irina Mihaela MATRAN Daniela Lucia MUNTEAN Cristina NICULAS Roxana Maria MARTIN-HADMAS Monica TARCEA
author_sort	Irina Mihaela MATRAN
title	Possible algorithms for determining adverse reactions caused by food supplements in Romania
title_short	Possible algorithms for determining adverse reactions caused by food supplements in Romania
title_full	Possible algorithms for determining adverse reactions caused by food supplements in Romania
title_fullStr	Possible algorithms for determining adverse reactions caused by food supplements in Romania
title_full_unstemmed	Possible algorithms for determining adverse reactions caused by food supplements in Romania
title_sort	possible algorithms for determining adverse reactions caused by food supplements in romania
publisher	Asociatia de Biosiguranta si Biosecuritate
publishDate	2021
url	https://doaj.org/article/b6fc1e8d0dd14889be701322bd2c526d
work_keys_str_mv	AT irinamihaelamatran possiblealgorithmsfordeterminingadversereactionscausedbyfoodsupplementsinromania AT danielaluciamuntean possiblealgorithmsfordeterminingadversereactionscausedbyfoodsupplementsinromania AT cristinaniculas possiblealgorithmsfordeterminingadversereactionscausedbyfoodsupplementsinromania AT roxanamariamartinhadmas possiblealgorithmsfordeterminingadversereactionscausedbyfoodsupplementsinromania AT monicatarcea possiblealgorithmsfordeterminingadversereactionscausedbyfoodsupplementsinromania
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Possible algorithms for determining adverse reactions caused by food supplements in Romania

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