Biological Effects of Anti-RANKL Antibody and Zoledronic Acid on Growth and Tooth Eruption in Growing Mice

Abstract The anti-bone resorptive drugs denosumab, an anti-human-RANKL antibody, and zoledronic acid (ZOL), a nitrogen-containing bisphosphonate, have recently been applied for treatment of pediatric patients with bone diseases, though details regarding their effects in growing children have yet to...

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Auteurs principaux: Motoki Isawa, Akiko Karakawa, Nobuhiro Sakai, Saki Nishina, Miku Kuritani, Masahiro Chatani, Takako Negishi-Koga, Masashi Sato, Mitsuko Inoue, Yukie Shimada, Masamichi Takami
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/b70533e1eb9249e487693f5b7a41ef4c
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