Decoding and reprogramming fungal iterative nonribosomal peptide synthetases
Nonribosomal peptides are important bioactive molecules that are synthetized by enzymes containing several catalytic domains. Here the authors describe the catalytic mechanism of fungal nonribosomal peptide synthetases and present an approach to modify these enzymes to produce specific nonribosomal...
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Nature Portfolio
2017
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oai:doaj.org-article:b708f35e78d94ae998b3ecbdff7a24a42021-12-02T17:06:10ZDecoding and reprogramming fungal iterative nonribosomal peptide synthetases10.1038/ncomms153492041-1723https://doaj.org/article/b708f35e78d94ae998b3ecbdff7a24a42017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15349https://doaj.org/toc/2041-1723Nonribosomal peptides are important bioactive molecules that are synthetized by enzymes containing several catalytic domains. Here the authors describe the catalytic mechanism of fungal nonribosomal peptide synthetases and present an approach to modify these enzymes to produce specific nonribosomal peptides.Dayu YuFuchao XuShuwei ZhangJixun ZhanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
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Science Q Dayu Yu Fuchao Xu Shuwei Zhang Jixun Zhan Decoding and reprogramming fungal iterative nonribosomal peptide synthetases |
description |
Nonribosomal peptides are important bioactive molecules that are synthetized by enzymes containing several catalytic domains. Here the authors describe the catalytic mechanism of fungal nonribosomal peptide synthetases and present an approach to modify these enzymes to produce specific nonribosomal peptides. |
format |
article |
author |
Dayu Yu Fuchao Xu Shuwei Zhang Jixun Zhan |
author_facet |
Dayu Yu Fuchao Xu Shuwei Zhang Jixun Zhan |
author_sort |
Dayu Yu |
title |
Decoding and reprogramming fungal iterative nonribosomal peptide synthetases |
title_short |
Decoding and reprogramming fungal iterative nonribosomal peptide synthetases |
title_full |
Decoding and reprogramming fungal iterative nonribosomal peptide synthetases |
title_fullStr |
Decoding and reprogramming fungal iterative nonribosomal peptide synthetases |
title_full_unstemmed |
Decoding and reprogramming fungal iterative nonribosomal peptide synthetases |
title_sort |
decoding and reprogramming fungal iterative nonribosomal peptide synthetases |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/b708f35e78d94ae998b3ecbdff7a24a4 |
work_keys_str_mv |
AT dayuyu decodingandreprogrammingfungaliterativenonribosomalpeptidesynthetases AT fuchaoxu decodingandreprogrammingfungaliterativenonribosomalpeptidesynthetases AT shuweizhang decodingandreprogrammingfungaliterativenonribosomalpeptidesynthetases AT jixunzhan decodingandreprogrammingfungaliterativenonribosomalpeptidesynthetases |
_version_ |
1718381695065915392 |