Decoding and reprogramming fungal iterative nonribosomal peptide synthetases

Decoding and reprogramming fungal iterative nonribosomal peptide synthetases

Nonribosomal peptides are important bioactive molecules that are synthetized by enzymes containing several catalytic domains. Here the authors describe the catalytic mechanism of fungal nonribosomal peptide synthetases and present an approach to modify these enzymes to produce specific nonribosomal...

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Main Authors: Dayu Yu, Fuchao Xu, Shuwei Zhang, Jixun Zhan
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Science
Q
Online Access:https://doaj.org/article/b708f35e78d94ae998b3ecbdff7a24a4
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spelling oai:doaj.org-article:b708f35e78d94ae998b3ecbdff7a24a42021-12-02T17:06:10ZDecoding and reprogramming fungal iterative nonribosomal peptide synthetases10.1038/ncomms153492041-1723https://doaj.org/article/b708f35e78d94ae998b3ecbdff7a24a42017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15349https://doaj.org/toc/2041-1723Nonribosomal peptides are important bioactive molecules that are synthetized by enzymes containing several catalytic domains. Here the authors describe the catalytic mechanism of fungal nonribosomal peptide synthetases and present an approach to modify these enzymes to produce specific nonribosomal peptides.Dayu YuFuchao XuShuwei ZhangJixun ZhanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dayu Yu
Fuchao Xu
Shuwei Zhang
Jixun Zhan
Decoding and reprogramming fungal iterative nonribosomal peptide synthetases
description Nonribosomal peptides are important bioactive molecules that are synthetized by enzymes containing several catalytic domains. Here the authors describe the catalytic mechanism of fungal nonribosomal peptide synthetases and present an approach to modify these enzymes to produce specific nonribosomal peptides.
format article
author Dayu Yu
Fuchao Xu
Shuwei Zhang
Jixun Zhan
author_facet Dayu Yu
Fuchao Xu
Shuwei Zhang
Jixun Zhan
author_sort Dayu Yu
title Decoding and reprogramming fungal iterative nonribosomal peptide synthetases
title_short Decoding and reprogramming fungal iterative nonribosomal peptide synthetases
title_full Decoding and reprogramming fungal iterative nonribosomal peptide synthetases
title_fullStr Decoding and reprogramming fungal iterative nonribosomal peptide synthetases
title_full_unstemmed Decoding and reprogramming fungal iterative nonribosomal peptide synthetases
title_sort decoding and reprogramming fungal iterative nonribosomal peptide synthetases
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/b708f35e78d94ae998b3ecbdff7a24a4
work_keys_str_mv AT dayuyu decodingandreprogrammingfungaliterativenonribosomalpeptidesynthetases
AT fuchaoxu decodingandreprogrammingfungaliterativenonribosomalpeptidesynthetases
AT shuweizhang decodingandreprogrammingfungaliterativenonribosomalpeptidesynthetases
AT jixunzhan decodingandreprogrammingfungaliterativenonribosomalpeptidesynthetases
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