Roles of active forms of vitamin D in supporting innate immune systems and in reducing excess inflammation in COVID-19

A reduced supply of micronutrient vitamin D leads to a more severe course of coronavirus infection (COVID-19). Vitamin D deficiency is combined with a decrease in innate antiviral immunity and excess of inflammation. Vitamin D supplementation stimulates the synthesis of antibacterial peptides and is...

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Autores principales:	Olga A. Gromova, Ivan I. Torshin, Alexander G. Chuchalin, Elena N. Kozhevnikova, Svetlana I. Malyavskaya
Formato:	article
Lenguaje:	RU
Publicado:	"Consilium Medicum" Publishing house 2021
Materias:	covid-19 antiviral immunity micronutrients alfacalcidol Medicine R
Acceso en línea:	https://doaj.org/article/b71999826eb54d3baf145145631e29d7
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id	oai:doaj.org-article:b71999826eb54d3baf145145631e29d7
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spelling	oai:doaj.org-article:b71999826eb54d3baf145145631e29d72021-12-01T12:22:36ZRoles of active forms of vitamin D in supporting innate immune systems and in reducing excess inflammation in COVID-190040-36602309-534210.26442/00403660.2021.08.200918https://doaj.org/article/b71999826eb54d3baf145145631e29d72021-08-01T00:00:00Zhttps://ter-arkhiv.ru/0040-3660/article/viewFile/79550/60166https://doaj.org/toc/0040-3660https://doaj.org/toc/2309-5342A reduced supply of micronutrient vitamin D leads to a more severe course of coronavirus infection (COVID-19). Vitamin D deficiency is combined with a decrease in innate antiviral immunity and excess of inflammation. Vitamin D supplementation stimulates the synthesis of antibacterial peptides and is important for weakening the cytokine storm, reducing excessive acute and chronic inflammation, and also for compensating for chronic comorbid pathologies. Active forms of vitamin D (alfacalcidol, etc.) are of particular importance for compensating for vitamin D deficiency in elderly patients, endocrine-immune dysfunction, sarcopenia, chronic renal failure (in which the metabolism of vitamin D in the kidneys is disturbed).Olga A. GromovaIvan I. TorshinAlexander G. ChuchalinElena N. KozhevnikovaSvetlana I. Malyavskaya"Consilium Medicum" Publishing housearticlecovid-19antiviral immunitymicronutrientsalfacalcidolMedicineRRUТерапевтический архив, Vol 93, Iss 8, Pp 948-953 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	covid-19 antiviral immunity micronutrients alfacalcidol Medicine R
spellingShingle	covid-19 antiviral immunity micronutrients alfacalcidol Medicine R Olga A. Gromova Ivan I. Torshin Alexander G. Chuchalin Elena N. Kozhevnikova Svetlana I. Malyavskaya Roles of active forms of vitamin D in supporting innate immune systems and in reducing excess inflammation in COVID-19
description	A reduced supply of micronutrient vitamin D leads to a more severe course of coronavirus infection (COVID-19). Vitamin D deficiency is combined with a decrease in innate antiviral immunity and excess of inflammation. Vitamin D supplementation stimulates the synthesis of antibacterial peptides and is important for weakening the cytokine storm, reducing excessive acute and chronic inflammation, and also for compensating for chronic comorbid pathologies. Active forms of vitamin D (alfacalcidol, etc.) are of particular importance for compensating for vitamin D deficiency in elderly patients, endocrine-immune dysfunction, sarcopenia, chronic renal failure (in which the metabolism of vitamin D in the kidneys is disturbed).
format	article
author	Olga A. Gromova Ivan I. Torshin Alexander G. Chuchalin Elena N. Kozhevnikova Svetlana I. Malyavskaya
author_facet	Olga A. Gromova Ivan I. Torshin Alexander G. Chuchalin Elena N. Kozhevnikova Svetlana I. Malyavskaya
author_sort	Olga A. Gromova
title	Roles of active forms of vitamin D in supporting innate immune systems and in reducing excess inflammation in COVID-19
title_short	Roles of active forms of vitamin D in supporting innate immune systems and in reducing excess inflammation in COVID-19
title_full	Roles of active forms of vitamin D in supporting innate immune systems and in reducing excess inflammation in COVID-19
title_fullStr	Roles of active forms of vitamin D in supporting innate immune systems and in reducing excess inflammation in COVID-19
title_full_unstemmed	Roles of active forms of vitamin D in supporting innate immune systems and in reducing excess inflammation in COVID-19
title_sort	roles of active forms of vitamin d in supporting innate immune systems and in reducing excess inflammation in covid-19
publisher	"Consilium Medicum" Publishing house
publishDate	2021
url	https://doaj.org/article/b71999826eb54d3baf145145631e29d7
work_keys_str_mv	AT olgaagromova rolesofactiveformsofvitamindinsupportinginnateimmunesystemsandinreducingexcessinflammationincovid19 AT ivanitorshin rolesofactiveformsofvitamindinsupportinginnateimmunesystemsandinreducingexcessinflammationincovid19 AT alexandergchuchalin rolesofactiveformsofvitamindinsupportinginnateimmunesystemsandinreducingexcessinflammationincovid19 AT elenankozhevnikova rolesofactiveformsofvitamindinsupportinginnateimmunesystemsandinreducingexcessinflammationincovid19 AT svetlanaimalyavskaya rolesofactiveformsofvitamindinsupportinginnateimmunesystemsandinreducingexcessinflammationincovid19
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Roles of active forms of vitamin D in supporting innate immune systems and in reducing excess inflammation in COVID-19

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