Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo

Connexins are components of gap junctions that link cells and allow intercellular communication. Here, the authors show that the Connexin 43 carboxy tail interacts with basic transcription factor-3, leading to nuclear translocation and direct regulation of N-cadherin expression and neural crest migr...

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Autores principales:	Maria Kotini, Elias H. Barriga, Jonathan Leslie, Marc Gentzel, Verena Rauschenberger, Alexandra Schambony, Roberto Mayor
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b71dd62dbf3b48999beb230913ac1eec
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spelling	oai:doaj.org-article:b71dd62dbf3b48999beb230913ac1eec2021-12-02T16:50:06ZGap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo10.1038/s41467-018-06368-x2041-1723https://doaj.org/article/b71dd62dbf3b48999beb230913ac1eec2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06368-xhttps://doaj.org/toc/2041-1723Connexins are components of gap junctions that link cells and allow intercellular communication. Here, the authors show that the Connexin 43 carboxy tail interacts with basic transcription factor-3, leading to nuclear translocation and direct regulation of N-cadherin expression and neural crest migration.Maria KotiniElias H. BarrigaJonathan LeslieMarc GentzelVerena RauschenbergerAlexandra SchambonyRoberto MayorNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maria Kotini Elias H. Barriga Jonathan Leslie Marc Gentzel Verena Rauschenberger Alexandra Schambony Roberto Mayor Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo
description	Connexins are components of gap junctions that link cells and allow intercellular communication. Here, the authors show that the Connexin 43 carboxy tail interacts with basic transcription factor-3, leading to nuclear translocation and direct regulation of N-cadherin expression and neural crest migration.
format	article
author	Maria Kotini Elias H. Barriga Jonathan Leslie Marc Gentzel Verena Rauschenberger Alexandra Schambony Roberto Mayor
author_facet	Maria Kotini Elias H. Barriga Jonathan Leslie Marc Gentzel Verena Rauschenberger Alexandra Schambony Roberto Mayor
author_sort	Maria Kotini
title	Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo
title_short	Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo
title_full	Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo
title_fullStr	Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo
title_full_unstemmed	Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo
title_sort	gap junction protein connexin-43 is a direct transcriptional regulator of n-cadherin in vivo
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/b71dd62dbf3b48999beb230913ac1eec
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Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo

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