Development of technological complex for production of compounded infusion admixtures in hospital pharmacies

The modern model of infusion pharmacotherapy in hospitals involves a process-based approach, the most important "input" of which is the manufacturing of infusion admixtures and the control of infusions preparation. In Russian hospitals, production of drug admixtures is carried out by nursi...

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Autores principales:	E. N. Mikhalevich, G. N. Kovalskaya
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2017
Materias:	compounded drug production infusion admixtures technological complex drug interaction Science Q
Acceso en línea:	https://doaj.org/article/b72356f6298c4dd7896db6e5d2cd10d9
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spelling	oai:doaj.org-article:b72356f6298c4dd7896db6e5d2cd10d92021-11-23T06:14:37ZDevelopment of technological complex for production of compounded infusion admixtures in hospital pharmacies2541-94202587-959610.12737/article_59f0360009a085.50048625https://doaj.org/article/b72356f6298c4dd7896db6e5d2cd10d92017-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/396https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The modern model of infusion pharmacotherapy in hospitals involves a process-based approach, the most important "input" of which is the manufacturing of infusion admixtures and the control of infusions preparation. In Russian hospitals, production of drug admixtures is carried out by nursing staff in inappropriate conditions and with equipment unappropriated for this type of activity. In accordance with the normative documentation, manufacturing of infusion admixtures should be reserved for hospital pharmacies. Only in pharmacies it is possible to organize a manufacture complex of infusion admixtures of adequate quality under aseptic conditions. For the extemporaneous manufacturing of infusion admixtures in hospital pharmacies of the Russian Federation we have developed technological complex, which included: development of information database "Interaction of injectable drugs"; development of technological schemes of manufacturing of infusion mixtures; selection of necessary equipment; development of a system of quality control of infusion admixtures. The information database is a search engine that allows to estimate the composition of the recipe on the compatibility of components. The typical scheme of production areas of hospital pharmacy allows you to place required for aseptic manufacturing equipment with minimal costs. Step by step instruction on mixing the components of the recipe eliminates contamination in product. The system of quality control confirms the high quality of infusion admixtures. Overall, this technological complex ensures quality, efficiency and safety provided to patients of the hospital infusion therapy.E. N. MikhalevichG. N. KovalskayaScientific Сentre for Family Health and Human Reproduction Problemsarticlecompounded drug productioninfusion admixturestechnological complexdrug interactionScienceQRUActa Biomedica Scientifica, Vol 2, Iss 3, Pp 82-86 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	compounded drug production infusion admixtures technological complex drug interaction Science Q
spellingShingle	compounded drug production infusion admixtures technological complex drug interaction Science Q E. N. Mikhalevich G. N. Kovalskaya Development of technological complex for production of compounded infusion admixtures in hospital pharmacies
description	The modern model of infusion pharmacotherapy in hospitals involves a process-based approach, the most important "input" of which is the manufacturing of infusion admixtures and the control of infusions preparation. In Russian hospitals, production of drug admixtures is carried out by nursing staff in inappropriate conditions and with equipment unappropriated for this type of activity. In accordance with the normative documentation, manufacturing of infusion admixtures should be reserved for hospital pharmacies. Only in pharmacies it is possible to organize a manufacture complex of infusion admixtures of adequate quality under aseptic conditions. For the extemporaneous manufacturing of infusion admixtures in hospital pharmacies of the Russian Federation we have developed technological complex, which included: development of information database "Interaction of injectable drugs"; development of technological schemes of manufacturing of infusion mixtures; selection of necessary equipment; development of a system of quality control of infusion admixtures. The information database is a search engine that allows to estimate the composition of the recipe on the compatibility of components. The typical scheme of production areas of hospital pharmacy allows you to place required for aseptic manufacturing equipment with minimal costs. Step by step instruction on mixing the components of the recipe eliminates contamination in product. The system of quality control confirms the high quality of infusion admixtures. Overall, this technological complex ensures quality, efficiency and safety provided to patients of the hospital infusion therapy.
format	article
author	E. N. Mikhalevich G. N. Kovalskaya
author_facet	E. N. Mikhalevich G. N. Kovalskaya
author_sort	E. N. Mikhalevich
title	Development of technological complex for production of compounded infusion admixtures in hospital pharmacies
title_short	Development of technological complex for production of compounded infusion admixtures in hospital pharmacies
title_full	Development of technological complex for production of compounded infusion admixtures in hospital pharmacies
title_fullStr	Development of technological complex for production of compounded infusion admixtures in hospital pharmacies
title_full_unstemmed	Development of technological complex for production of compounded infusion admixtures in hospital pharmacies
title_sort	development of technological complex for production of compounded infusion admixtures in hospital pharmacies
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2017
url	https://doaj.org/article/b72356f6298c4dd7896db6e5d2cd10d9
work_keys_str_mv	AT enmikhalevich developmentoftechnologicalcomplexforproductionofcompoundedinfusionadmixturesinhospitalpharmacies AT gnkovalskaya developmentoftechnologicalcomplexforproductionofcompoundedinfusionadmixturesinhospitalpharmacies
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Development of technological complex for production of compounded infusion admixtures in hospital pharmacies

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