Renal Acoustic Radiation Force Impulse Elastography in Hypertensive Nephroangiosclerosis Patients

<b>Objective:</b> Hypertensive nephroangiosclerosis (HN) represents the second most common cause of chronic kidney disease. Kidney damage secondary to high blood pressure favors the appearance of serum and urinary changes, but also imaging, highlighted by ultrasonography (B-mode, Doppler...

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Autores principales:	Alexandru Caraba, Andreea Munteanu, Stela Iurciuc, Mircea Iurciuc
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	acoustic radiation force impulse elastography hypertensive nephroangiosclerosis intrarenal resistive index Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/b726e52dcfed43fa9eba082f44c4b1aa
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spelling	oai:doaj.org-article:b726e52dcfed43fa9eba082f44c4b1aa2021-11-25T16:33:07ZRenal Acoustic Radiation Force Impulse Elastography in Hypertensive Nephroangiosclerosis Patients10.3390/app1122106122076-3417https://doaj.org/article/b726e52dcfed43fa9eba082f44c4b1aa2021-11-01T00:00:00Zhttps://www.mdpi.com/2076-3417/11/22/10612https://doaj.org/toc/2076-3417<b>Objective:</b> Hypertensive nephroangiosclerosis (HN) represents the second most common cause of chronic kidney disease. Kidney damage secondary to high blood pressure favors the appearance of serum and urinary changes, but also imaging, highlighted by ultrasonography (B-mode, Doppler, Acoustic Radiation Force Impulse Elastography). Acoustic Radiation Force Impulse Elastography (ARFI) represents a new imagistic method which characterizes renal stiffness in the form of shear wave velocity (SWV). <b>Aim:</b> This study aims to investigate renal stiffness in HN patients, and to assess the correlations between it and urinary albumin/creatinine ratio (UACR), estimated glomerular filtration rate (eGFR), and intrarenal resistive index (RRI). <b>Material and Methods:</b> This cross-sectional study was performed on a group of 80 HN patients and 50 healthy, sex and age-matched, as controls. UACR (urinary immunoturbidimetry), eGFR (Jaffe method), RRI, and renal SWV (Siemens Acuson 2000) were determined in all patients and controls. Data were expressed as mean ± standard deviation. Statistical analysis was done by means Pearson’s test and t-Student test, <i>p</i> values of less than 0.05 were considered statistically significant. <b>Results:</b> UACR, eGFR, RRI and SWV showed statistically significant differences between the HN patients and controls (<i>p</i> < 0.0001). In the hypertensive patients group, statistically significant correlations were observed between the SWV and UACR (r = −0.7633, <i>p</i> < 0.00001), eGFR (r = 0.7822, <i>p</i> = 0.00001), and RRI (r = −0.7978, <i>p</i> = 0.00001). <b>Conclusions:</b> Kidney sonoelastography characterizes imagistically the existence of intrarenal lesions associated with essential hypertension, offering a new diagnosis method for these patients.Alexandru CarabaAndreea MunteanuStela IurciucMircea IurciucMDPI AGarticleacoustic radiation force impulse elastographyhypertensive nephroangiosclerosisintrarenal resistive indexTechnologyTEngineering (General). Civil engineering (General)TA1-2040Biology (General)QH301-705.5PhysicsQC1-999ChemistryQD1-999ENApplied Sciences, Vol 11, Iss 10612, p 10612 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	acoustic radiation force impulse elastography hypertensive nephroangiosclerosis intrarenal resistive index Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999
spellingShingle	acoustic radiation force impulse elastography hypertensive nephroangiosclerosis intrarenal resistive index Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999 Alexandru Caraba Andreea Munteanu Stela Iurciuc Mircea Iurciuc Renal Acoustic Radiation Force Impulse Elastography in Hypertensive Nephroangiosclerosis Patients
description	<b>Objective:</b> Hypertensive nephroangiosclerosis (HN) represents the second most common cause of chronic kidney disease. Kidney damage secondary to high blood pressure favors the appearance of serum and urinary changes, but also imaging, highlighted by ultrasonography (B-mode, Doppler, Acoustic Radiation Force Impulse Elastography). Acoustic Radiation Force Impulse Elastography (ARFI) represents a new imagistic method which characterizes renal stiffness in the form of shear wave velocity (SWV). <b>Aim:</b> This study aims to investigate renal stiffness in HN patients, and to assess the correlations between it and urinary albumin/creatinine ratio (UACR), estimated glomerular filtration rate (eGFR), and intrarenal resistive index (RRI). <b>Material and Methods:</b> This cross-sectional study was performed on a group of 80 HN patients and 50 healthy, sex and age-matched, as controls. UACR (urinary immunoturbidimetry), eGFR (Jaffe method), RRI, and renal SWV (Siemens Acuson 2000) were determined in all patients and controls. Data were expressed as mean ± standard deviation. Statistical analysis was done by means Pearson’s test and t-Student test, <i>p</i> values of less than 0.05 were considered statistically significant. <b>Results:</b> UACR, eGFR, RRI and SWV showed statistically significant differences between the HN patients and controls (<i>p</i> < 0.0001). In the hypertensive patients group, statistically significant correlations were observed between the SWV and UACR (r = −0.7633, <i>p</i> < 0.00001), eGFR (r = 0.7822, <i>p</i> = 0.00001), and RRI (r = −0.7978, <i>p</i> = 0.00001). <b>Conclusions:</b> Kidney sonoelastography characterizes imagistically the existence of intrarenal lesions associated with essential hypertension, offering a new diagnosis method for these patients.
format	article
author	Alexandru Caraba Andreea Munteanu Stela Iurciuc Mircea Iurciuc
author_facet	Alexandru Caraba Andreea Munteanu Stela Iurciuc Mircea Iurciuc
author_sort	Alexandru Caraba
title	Renal Acoustic Radiation Force Impulse Elastography in Hypertensive Nephroangiosclerosis Patients
title_short	Renal Acoustic Radiation Force Impulse Elastography in Hypertensive Nephroangiosclerosis Patients
title_full	Renal Acoustic Radiation Force Impulse Elastography in Hypertensive Nephroangiosclerosis Patients
title_fullStr	Renal Acoustic Radiation Force Impulse Elastography in Hypertensive Nephroangiosclerosis Patients
title_full_unstemmed	Renal Acoustic Radiation Force Impulse Elastography in Hypertensive Nephroangiosclerosis Patients
title_sort	renal acoustic radiation force impulse elastography in hypertensive nephroangiosclerosis patients
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/b726e52dcfed43fa9eba082f44c4b1aa
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Renal Acoustic Radiation Force Impulse Elastography in Hypertensive Nephroangiosclerosis Patients

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