Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance

Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance

Abstract Expression of the chromatin-associated protein HMGA2 correlates with progression, metastasis and therapy resistance in pancreatic ductal adenocarcinoma (PDAC). Hmga2 has also been identified as a marker of a transient subpopulation of PDAC cells that has increased metastatic ability. Here,...

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Bibliographic Details
Main Authors: Shin-Heng Chiou, Madeleine Dorsch, Eva Kusch, Santiago Naranjo, Margaret M. Kozak, Albert C. Koong, Monte M. Winslow, Barbara M. Grüner
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
High Mobility Group A2 (HMGA2)
Pancreatic Ductal Adenocarcinoma (PDAC)
HMGA2 Protein
PDAC Cells
Murine PDAC
Medicine
R
Science
Q
Online Access:https://doaj.org/article/b72834b1a36a49d0bfd2fb6d72fac298
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https://doaj.org/article/b72834b1a36a49d0bfd2fb6d72fac298

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