Challenges in Quantifying Cytosine Methylation in the HIV Provirus

ABSTRACT DNA methylation is an epigenetic mechanism most commonly associated with transcriptional repression. While it is clear that DNA methylation can silence HIV proviral expression in in vitro latency models, its correlation with HIV persistence and expression in vivo is ambiguous, particularly...

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Autores principales: Sarah A. LaMere, Antoine Chaillon, Christina Huynh, Davey M. Smith, Sara Gianella
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/b7390ba0885f4d55bdc9305fde4be517
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