Progression to vascular dementia of patients with mild cognitive impairment: relevance of mild parkinsonian signs

Marco Mauri, Simona Corbetta, Cristina Pianezzola, Elena Ambrosoni, Giulio Riboldazzi, Giorgio BonoUnit of Neurology, Dept of Clinical Medicine, Ospedale di Circolo &ndash; University of Insubria, Varese, ItalyAbstract: Mild parkinsonian signs (MPS) may be found among patients presenting wit...

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Autores principales:	Marco Mauri, Simona Corbetta, Cristina Pianezzola, Elena Ambrosoni, Giulio Riboldazzi, Giorgio Bono
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2008
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/b73b0d9b0b5141c9946dd3374666fea4
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spelling	oai:doaj.org-article:b73b0d9b0b5141c9946dd3374666fea42021-12-02T03:48:40ZProgression to vascular dementia of patients with mild cognitive impairment: relevance of mild parkinsonian signs1176-63281178-2021https://doaj.org/article/b73b0d9b0b5141c9946dd3374666fea42008-10-01T00:00:00Zhttp://www.dovepress.com/progression-to-vascular-dementia-of-patients-with-mild-cognitive-impai-a2522https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Marco Mauri, Simona Corbetta, Cristina Pianezzola, Elena Ambrosoni, Giulio Riboldazzi, Giorgio BonoUnit of Neurology, Dept of Clinical Medicine, Ospedale di Circolo &ndash; University of Insubria, Varese, ItalyAbstract: Mild parkinsonian signs (MPS) may be found among patients presenting with mild cognitive impairment (MCI), but few data are available about the relation of these signs with the prospective risk for dementia. Our retrospective investigation considered a case-series of 119 MCI subjects followed over a three-year period: their baseline clinical picture has been analyzed in search of correlation between the cognito-motor profile and the final diagnosis. The population included 66 patients with amnesic MCI and 53 with an involvement of other cognitive areas (nonamnesic MCI). MPS were detected in 22 subjects (18.5%). At the first observation, MPS cases showed an higher frequency of nonamnesic MCI and more pronounced deficits at the Trail Making Test (p &lt;&nbsp;0.05). After a three-year follow-up, 48 patients had converted to dementia. The presence of MPS at the baseline evaluation was significantly related to the development of a vascular-type dementia. The study investigates the association between MPS and MCI and might indicate for these cases a greater risk for an involvement of executive functions and the subsequent development of vascular dementia.Keywords: mild cognitive impairment, dementia, cerebrovascular disease, parkinsonism Marco MauriSimona CorbettaCristina PianezzolaElena AmbrosoniGiulio RiboldazziGiorgio BonoDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2008, Iss Issue 6, Pp 1267-1271 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Marco Mauri Simona Corbetta Cristina Pianezzola Elena Ambrosoni Giulio Riboldazzi Giorgio Bono Progression to vascular dementia of patients with mild cognitive impairment: relevance of mild parkinsonian signs
description	Marco Mauri, Simona Corbetta, Cristina Pianezzola, Elena Ambrosoni, Giulio Riboldazzi, Giorgio BonoUnit of Neurology, Dept of Clinical Medicine, Ospedale di Circolo &ndash; University of Insubria, Varese, ItalyAbstract: Mild parkinsonian signs (MPS) may be found among patients presenting with mild cognitive impairment (MCI), but few data are available about the relation of these signs with the prospective risk for dementia. Our retrospective investigation considered a case-series of 119 MCI subjects followed over a three-year period: their baseline clinical picture has been analyzed in search of correlation between the cognito-motor profile and the final diagnosis. The population included 66 patients with amnesic MCI and 53 with an involvement of other cognitive areas (nonamnesic MCI). MPS were detected in 22 subjects (18.5%). At the first observation, MPS cases showed an higher frequency of nonamnesic MCI and more pronounced deficits at the Trail Making Test (p &lt;&nbsp;0.05). After a three-year follow-up, 48 patients had converted to dementia. The presence of MPS at the baseline evaluation was significantly related to the development of a vascular-type dementia. The study investigates the association between MPS and MCI and might indicate for these cases a greater risk for an involvement of executive functions and the subsequent development of vascular dementia.Keywords: mild cognitive impairment, dementia, cerebrovascular disease, parkinsonism
format	article
author	Marco Mauri Simona Corbetta Cristina Pianezzola Elena Ambrosoni Giulio Riboldazzi Giorgio Bono
author_facet	Marco Mauri Simona Corbetta Cristina Pianezzola Elena Ambrosoni Giulio Riboldazzi Giorgio Bono
author_sort	Marco Mauri
title	Progression to vascular dementia of patients with mild cognitive impairment: relevance of mild parkinsonian signs
title_short	Progression to vascular dementia of patients with mild cognitive impairment: relevance of mild parkinsonian signs
title_full	Progression to vascular dementia of patients with mild cognitive impairment: relevance of mild parkinsonian signs
title_fullStr	Progression to vascular dementia of patients with mild cognitive impairment: relevance of mild parkinsonian signs
title_full_unstemmed	Progression to vascular dementia of patients with mild cognitive impairment: relevance of mild parkinsonian signs
title_sort	progression to vascular dementia of patients with mild cognitive impairment: relevance of mild parkinsonian signs
publisher	Dove Medical Press
publishDate	2008
url	https://doaj.org/article/b73b0d9b0b5141c9946dd3374666fea4
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Progression to vascular dementia of patients with mild cognitive impairment: relevance of mild parkinsonian signs

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