Genotype–covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model
Complex traits are often influenced by genetic and non-genetic factors (such as environmental exposures), which are themselves interconnected. Here, the authors develop a method for disentangling genotype–covariate correlation and interaction, and investigate their effects on estimating statistical...
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Autores principales: | Guiyan Ni, Julius van der Werf, Xuan Zhou, Elina Hyppönen, Naomi R. Wray, S. Hong Lee |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/b73da63376ad4ac8b1df5ee607da5804 |
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