Nuclear transporter Importin-13 plays a key role in the oxidative stress transcriptional response

Importin superfamily member IPO13 mediates nuclear transport bidirectionally. Here the authors delineate the transcriptome of wild-type and IPO13-knockout mouse embryonic stem cells, revealing IPO13’s key role in the oxidative stress response through targeted transport of specific transcription fact...

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Autores principales:	K. A. Gajewska, H. Lescesen, M. Ramialison, K. M. Wagstaff, D. A. Jans
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b73e2860ff77442a8c82e2e76349fef2
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spelling	oai:doaj.org-article:b73e2860ff77442a8c82e2e76349fef22021-12-02T18:37:16ZNuclear transporter Importin-13 plays a key role in the oxidative stress transcriptional response10.1038/s41467-021-26125-x2041-1723https://doaj.org/article/b73e2860ff77442a8c82e2e76349fef22021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26125-xhttps://doaj.org/toc/2041-1723Importin superfamily member IPO13 mediates nuclear transport bidirectionally. Here the authors delineate the transcriptome of wild-type and IPO13-knockout mouse embryonic stem cells, revealing IPO13’s key role in the oxidative stress response through targeted transport of specific transcription factors.K. A. GajewskaH. LescesenM. RamialisonK. M. WagstaffD. A. JansNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q K. A. Gajewska H. Lescesen M. Ramialison K. M. Wagstaff D. A. Jans Nuclear transporter Importin-13 plays a key role in the oxidative stress transcriptional response
description	Importin superfamily member IPO13 mediates nuclear transport bidirectionally. Here the authors delineate the transcriptome of wild-type and IPO13-knockout mouse embryonic stem cells, revealing IPO13’s key role in the oxidative stress response through targeted transport of specific transcription factors.
format	article
author	K. A. Gajewska H. Lescesen M. Ramialison K. M. Wagstaff D. A. Jans
author_facet	K. A. Gajewska H. Lescesen M. Ramialison K. M. Wagstaff D. A. Jans
author_sort	K. A. Gajewska
title	Nuclear transporter Importin-13 plays a key role in the oxidative stress transcriptional response
title_short	Nuclear transporter Importin-13 plays a key role in the oxidative stress transcriptional response
title_full	Nuclear transporter Importin-13 plays a key role in the oxidative stress transcriptional response
title_fullStr	Nuclear transporter Importin-13 plays a key role in the oxidative stress transcriptional response
title_full_unstemmed	Nuclear transporter Importin-13 plays a key role in the oxidative stress transcriptional response
title_sort	nuclear transporter importin-13 plays a key role in the oxidative stress transcriptional response
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b73e2860ff77442a8c82e2e76349fef2
work_keys_str_mv	AT kagajewska nucleartransporterimportin13playsakeyroleintheoxidativestresstranscriptionalresponse AT hlescesen nucleartransporterimportin13playsakeyroleintheoxidativestresstranscriptionalresponse AT mramialison nucleartransporterimportin13playsakeyroleintheoxidativestresstranscriptionalresponse AT kmwagstaff nucleartransporterimportin13playsakeyroleintheoxidativestresstranscriptionalresponse AT dajans nucleartransporterimportin13playsakeyroleintheoxidativestresstranscriptionalresponse
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Nuclear transporter Importin-13 plays a key role in the oxidative stress transcriptional response

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