Concerted localization-resets precede YAP-dependent transcription

The transcriptional regulator YAP shuttles rapidly between the cytoplasm and nucleus, but whether and how dynamics such as amplitude and frequency affect target gene transcription is unclear. Here, using live imaging of endogenous YAP and target-gene transcription, the authors show that YAP-dependen...

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Autores principales: J. Matthew Franklin, Rajarshi P. Ghosh, Quanming Shi, Michael P. Reddick, Jan T. Liphardt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b74055e5260d4791ba53349afa233f25
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