Concerted localization-resets precede YAP-dependent transcription

The transcriptional regulator YAP shuttles rapidly between the cytoplasm and nucleus, but whether and how dynamics such as amplitude and frequency affect target gene transcription is unclear. Here, using live imaging of endogenous YAP and target-gene transcription, the authors show that YAP-dependen...

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Bibliographic Details
Main Authors: J. Matthew Franklin, Rajarshi P. Ghosh, Quanming Shi, Michael P. Reddick, Jan T. Liphardt
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Q
Online Access:https://doaj.org/article/b74055e5260d4791ba53349afa233f25
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