Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

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Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

Schizophrenia (SCZ) risk is influenced by genetic and environmental factors. Here, the authors develop a statistical method for analyzing gene-by-environment effects in SCZ risk across Denmark with fine spatial resolution.

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Detalles Bibliográficos
Autores principales:	Chun Chieh Fan, John J. McGrath, Vivek Appadurai, Alfonso Buil, Michael J. Gandal, Andrew J. Schork, Preben Bo Mortensen, Esben Agerbo, Sandy A. Geschwind, Daniel Geschwind, Thomas Werge, Wesley K. Thompson, Carsten Bøcker Pedersen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b7449a7728a54638a2286add760066c3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Descripción
Sumario:	Schizophrenia (SCZ) risk is influenced by genetic and environmental factors. Here, the authors develop a statistical method for analyzing gene-by-environment effects in SCZ risk across Denmark with fine spatial resolution.