Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

Schizophrenia (SCZ) risk is influenced by genetic and environmental factors. Here, the authors develop a statistical method for analyzing gene-by-environment effects in SCZ risk across Denmark with fine spatial resolution.

Guardado en:

Detalles Bibliográficos
Autores principales:	Chun Chieh Fan, John J. McGrath, Vivek Appadurai, Alfonso Buil, Michael J. Gandal, Andrew J. Schork, Preben Bo Mortensen, Esben Agerbo, Sandy A. Geschwind, Daniel Geschwind, Thomas Werge, Wesley K. Thompson, Carsten Bøcker Pedersen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b7449a7728a54638a2286add760066c3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b7449a7728a54638a2286add760066c3
record_format	dspace
spelling	oai:doaj.org-article:b7449a7728a54638a2286add760066c32021-12-02T14:40:44ZSpatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia10.1038/s41467-018-07708-72041-1723https://doaj.org/article/b7449a7728a54638a2286add760066c32018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07708-7https://doaj.org/toc/2041-1723Schizophrenia (SCZ) risk is influenced by genetic and environmental factors. Here, the authors develop a statistical method for analyzing gene-by-environment effects in SCZ risk across Denmark with fine spatial resolution.Chun Chieh FanJohn J. McGrathVivek AppaduraiAlfonso BuilMichael J. GandalAndrew J. SchorkPreben Bo MortensenEsben AgerboSandy A. GeschwindDaniel GeschwindThomas WergeWesley K. ThompsonCarsten Bøcker PedersenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chun Chieh Fan John J. McGrath Vivek Appadurai Alfonso Buil Michael J. Gandal Andrew J. Schork Preben Bo Mortensen Esben Agerbo Sandy A. Geschwind Daniel Geschwind Thomas Werge Wesley K. Thompson Carsten Bøcker Pedersen Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia
description	Schizophrenia (SCZ) risk is influenced by genetic and environmental factors. Here, the authors develop a statistical method for analyzing gene-by-environment effects in SCZ risk across Denmark with fine spatial resolution.
format	article
author	Chun Chieh Fan John J. McGrath Vivek Appadurai Alfonso Buil Michael J. Gandal Andrew J. Schork Preben Bo Mortensen Esben Agerbo Sandy A. Geschwind Daniel Geschwind Thomas Werge Wesley K. Thompson Carsten Bøcker Pedersen
author_facet	Chun Chieh Fan John J. McGrath Vivek Appadurai Alfonso Buil Michael J. Gandal Andrew J. Schork Preben Bo Mortensen Esben Agerbo Sandy A. Geschwind Daniel Geschwind Thomas Werge Wesley K. Thompson Carsten Bøcker Pedersen
author_sort	Chun Chieh Fan
title	Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia
title_short	Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia
title_full	Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia
title_fullStr	Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia
title_full_unstemmed	Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia
title_sort	spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/b7449a7728a54638a2286add760066c3
work_keys_str_mv	AT chunchiehfan spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia AT johnjmcgrath spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia AT vivekappadurai spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia AT alfonsobuil spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia AT michaeljgandal spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia AT andrewjschork spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia AT prebenbomortensen spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia AT esbenagerbo spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia AT sandyageschwind spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia AT danielgeschwind spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia AT thomaswerge spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia AT wesleykthompson spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia AT carstenbøckerpedersen spatialfinemappingforgenebyenvironmenteffectsidentifiesriskhotspotsforschizophrenia
_version_	1718390193028857856

Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

Ejemplares similares