High SARS-CoV-2 seroprevalence in persons experiencing homelessness and shelter workers from a day-shelter in São Paulo, Brazil.

Brazil presents one of the highest COVID-19 death tolls in the world. The initial SARS-CoV-2 epicenter was São Paulo city. As of 2019, the homeless population of São Paulo city was estimated at 24,344 individuals, the largest national homeless population. The present study aimed to concomitantly ass...

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Autores principales:	Anahi Chechia do Couto, Louise Bach Kmetiuk, Ruana Renostro Delai, Ana Pérola Drulla Brandão, Cairo Oliveira Monteiro, Luciana Helena Antoniassi da Silva, Camila Soares, Alexandre Campos Banari, Renato van Wilpe Bach, Christina Pettan-Brewer, Andrea Pires Dos Santos, Ana Marcia Sá Guimarães, Danielle Bruna Leal Oliveira, Edison Luiz Durigon, Alexander Welker Biondo
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/b74846aa9b9c4f23aadafa95b6f2acfa
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spelling	oai:doaj.org-article:b74846aa9b9c4f23aadafa95b6f2acfa2021-12-02T20:23:34ZHigh SARS-CoV-2 seroprevalence in persons experiencing homelessness and shelter workers from a day-shelter in São Paulo, Brazil.1935-27271935-273510.1371/journal.pntd.0009754https://doaj.org/article/b74846aa9b9c4f23aadafa95b6f2acfa2021-10-01T00:00:00Zhttps://doi.org/10.1371/journal.pntd.0009754https://doaj.org/toc/1935-2727https://doaj.org/toc/1935-2735Brazil presents one of the highest COVID-19 death tolls in the world. The initial SARS-CoV-2 epicenter was São Paulo city. As of 2019, the homeless population of São Paulo city was estimated at 24,344 individuals, the largest national homeless population. The present study aimed to concomitantly assess the molecular and serological prevalence and associated risk factors of SARS-CoV-2 infection in a homeless population and related shelter workers from a day-shelter. Serum samples, nasopharyngeal and oropharyngeal swabs of persons who are homeless and shelter workers collected from August 25th to 27th, 2020 were tested for the presence of anti-SARS-CoV-2 IgM and IgG antibodies by ELISA and SARS-CoV-2 RNA by RT-qPCR, respectively. All swab samples tested negative by RT-qPCR. Seropositivity of IgM and IgG was 5/203 (2.5%) and 111/203 (54.7%) in persons who are homeless, and 5/87 (5.7%) and 41/87 (47.1%) in shelter workers, respectively, with no statistical differences between groups. The high seroprevalence found herein indicates early environmental and urban spreading of SARS-CoV-2, associated with sociodemographic and economic vulnerability.Anahi Chechia do CoutoLouise Bach KmetiukRuana Renostro DelaiAna Pérola Drulla BrandãoCairo Oliveira MonteiroLuciana Helena Antoniassi da SilvaCamila SoaresAlexandre Campos BanariRenato van Wilpe BachChristina Pettan-BrewerAndrea Pires Dos SantosAna Marcia Sá GuimarãesDanielle Bruna Leal OliveiraEdison Luiz DurigonAlexander Welker BiondoPublic Library of Science (PLoS)articleArctic medicine. Tropical medicineRC955-962Public aspects of medicineRA1-1270ENPLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009754 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270
spellingShingle	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Anahi Chechia do Couto Louise Bach Kmetiuk Ruana Renostro Delai Ana Pérola Drulla Brandão Cairo Oliveira Monteiro Luciana Helena Antoniassi da Silva Camila Soares Alexandre Campos Banari Renato van Wilpe Bach Christina Pettan-Brewer Andrea Pires Dos Santos Ana Marcia Sá Guimarães Danielle Bruna Leal Oliveira Edison Luiz Durigon Alexander Welker Biondo High SARS-CoV-2 seroprevalence in persons experiencing homelessness and shelter workers from a day-shelter in São Paulo, Brazil.
description	Brazil presents one of the highest COVID-19 death tolls in the world. The initial SARS-CoV-2 epicenter was São Paulo city. As of 2019, the homeless population of São Paulo city was estimated at 24,344 individuals, the largest national homeless population. The present study aimed to concomitantly assess the molecular and serological prevalence and associated risk factors of SARS-CoV-2 infection in a homeless population and related shelter workers from a day-shelter. Serum samples, nasopharyngeal and oropharyngeal swabs of persons who are homeless and shelter workers collected from August 25th to 27th, 2020 were tested for the presence of anti-SARS-CoV-2 IgM and IgG antibodies by ELISA and SARS-CoV-2 RNA by RT-qPCR, respectively. All swab samples tested negative by RT-qPCR. Seropositivity of IgM and IgG was 5/203 (2.5%) and 111/203 (54.7%) in persons who are homeless, and 5/87 (5.7%) and 41/87 (47.1%) in shelter workers, respectively, with no statistical differences between groups. The high seroprevalence found herein indicates early environmental and urban spreading of SARS-CoV-2, associated with sociodemographic and economic vulnerability.
format	article
author	Anahi Chechia do Couto Louise Bach Kmetiuk Ruana Renostro Delai Ana Pérola Drulla Brandão Cairo Oliveira Monteiro Luciana Helena Antoniassi da Silva Camila Soares Alexandre Campos Banari Renato van Wilpe Bach Christina Pettan-Brewer Andrea Pires Dos Santos Ana Marcia Sá Guimarães Danielle Bruna Leal Oliveira Edison Luiz Durigon Alexander Welker Biondo
author_facet	Anahi Chechia do Couto Louise Bach Kmetiuk Ruana Renostro Delai Ana Pérola Drulla Brandão Cairo Oliveira Monteiro Luciana Helena Antoniassi da Silva Camila Soares Alexandre Campos Banari Renato van Wilpe Bach Christina Pettan-Brewer Andrea Pires Dos Santos Ana Marcia Sá Guimarães Danielle Bruna Leal Oliveira Edison Luiz Durigon Alexander Welker Biondo
author_sort	Anahi Chechia do Couto
title	High SARS-CoV-2 seroprevalence in persons experiencing homelessness and shelter workers from a day-shelter in São Paulo, Brazil.
title_short	High SARS-CoV-2 seroprevalence in persons experiencing homelessness and shelter workers from a day-shelter in São Paulo, Brazil.
title_full	High SARS-CoV-2 seroprevalence in persons experiencing homelessness and shelter workers from a day-shelter in São Paulo, Brazil.
title_fullStr	High SARS-CoV-2 seroprevalence in persons experiencing homelessness and shelter workers from a day-shelter in São Paulo, Brazil.
title_full_unstemmed	High SARS-CoV-2 seroprevalence in persons experiencing homelessness and shelter workers from a day-shelter in São Paulo, Brazil.
title_sort	high sars-cov-2 seroprevalence in persons experiencing homelessness and shelter workers from a day-shelter in são paulo, brazil.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/b74846aa9b9c4f23aadafa95b6f2acfa
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High SARS-CoV-2 seroprevalence in persons experiencing homelessness and shelter workers from a day-shelter in São Paulo, Brazil.

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