ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE

Abstract. Immunopathological mechanisms of hemorrhagic fever with renal syndrome (HFRS) are very complex and are recognized as the cause of the basic pathophysiological abnormalities in this infection. In this report the results of investigation of IL12р70 and IL12р40 levels in serum of 22 patients...

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Autores principales:	L. Yu. Pereverten, E. V. Markelova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	immunopathegenesis cellular immunity hemorrhagic fever with renal syndrome Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/b74bce08777f4109bba8d4eea489b2d8
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spelling	oai:doaj.org-article:b74bce08777f4109bba8d4eea489b2d82021-11-18T08:03:41ZASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE1563-06252313-741X10.15789/1563-0625-2005-1-89-92https://doaj.org/article/b74bce08777f4109bba8d4eea489b2d82014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/442https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Immunopathological mechanisms of hemorrhagic fever with renal syndrome (HFRS) are very complex and are recognized as the cause of the basic pathophysiological abnormalities in this infection. In this report the results of investigation of IL12р70 and IL12р40 levels in serum of 22 patients with HFRS of different severity in dynamics of illness have been stated. High activity of IL12р70 in the acute phase of HFRS, associated with serotype Seoul virus has been determined. Probably, the influence of the other factors of immune system along with IL12р40 promoted the development of relative failure of cellular immunity in HFRS. (Med. Immunol., 2005, vol.7, № 1, pp 89592)L. Yu. PerevertenE. V. MarkelovaSPb RAACIarticleimmunopathegenesiscellular immunityhemorrhagic fever with renal syndromeImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 7, Iss 1, Pp 89-92 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	immunopathegenesis cellular immunity hemorrhagic fever with renal syndrome Immunologic diseases. Allergy RC581-607
spellingShingle	immunopathegenesis cellular immunity hemorrhagic fever with renal syndrome Immunologic diseases. Allergy RC581-607 L. Yu. Pereverten E. V. Markelova ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE
description	Abstract. Immunopathological mechanisms of hemorrhagic fever with renal syndrome (HFRS) are very complex and are recognized as the cause of the basic pathophysiological abnormalities in this infection. In this report the results of investigation of IL12р70 and IL12р40 levels in serum of 22 patients with HFRS of different severity in dynamics of illness have been stated. High activity of IL12р70 in the acute phase of HFRS, associated with serotype Seoul virus has been determined. Probably, the influence of the other factors of immune system along with IL12р40 promoted the development of relative failure of cellular immunity in HFRS. (Med. Immunol., 2005, vol.7, № 1, pp 89592)
format	article
author	L. Yu. Pereverten E. V. Markelova
author_facet	L. Yu. Pereverten E. V. Markelova
author_sort	L. Yu. Pereverten
title	ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE
title_short	ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE
title_full	ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE
title_fullStr	ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE
title_full_unstemmed	ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE
title_sort	assesment of il–12 activity in patients with hemorrhagic fever with renal syndrome associated with seoul serotype
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/b74bce08777f4109bba8d4eea489b2d8
work_keys_str_mv	AT lyupereverten assesmentofil12activityinpatientswithhemorrhagicfeverwithrenalsyndromeassociatedwithseoulserotype AT evmarkelova assesmentofil12activityinpatientswithhemorrhagicfeverwithrenalsyndromeassociatedwithseoulserotype
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ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE

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