Development of highly efficient platinum catalysts for hydroalkoxylation and hydroamination of unactivated alkenes

The direct addition of an O–H (hydroalkoxylation) or an N–H (hydroamination) bond across an alkene is a useful strategy to access biologically relevant heterocycles. Here, the authors report “donor–acceptor”-type platinum catalysts that are effective for both hydroalkoxylation and hydroamination of...

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Autores principales: Yali Zhou, Xingjun Xu, Hongwei Sun, Guanyu Tao, Xiao-Yong Chang, Xiangyou Xing, Bo Chen, Chen Xu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b7558009dee04f8caca8209b803af4dc
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Sumario:The direct addition of an O–H (hydroalkoxylation) or an N–H (hydroamination) bond across an alkene is a useful strategy to access biologically relevant heterocycles. Here, the authors report “donor–acceptor”-type platinum catalysts that are effective for both hydroalkoxylation and hydroamination of unactivated alkenes, with broad substrate scope and use of mild conditions.