Association of Growth Velocity with Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Children with a Vegan Diet

Background: The vegan diet in children provides the benefit of reducing the risk of being overweight and improving the fat profile. The risk that can occur in the provision of a vegan diet in children is anthropometric size below reference and low caloric intake. Growth hormone (GH) and Insulin like...

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Autores principales:	Arie Purwana, Budiono Budiono, Jose RL Batubara, Muhammad Faizi
Formato:	article
Lenguaje:	EN
Publicado:	Diponegoro University 2020
Materias:	igf-1 igfbp-3 growth velocity Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/b767ba73f00d4cef854726d083eb992d
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spelling	oai:doaj.org-article:b767ba73f00d4cef854726d083eb992d2021-11-05T16:47:32ZAssociation of Growth Velocity with Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Children with a Vegan Diet2503-217810.14710/jbtr.v6i1.5474https://doaj.org/article/b767ba73f00d4cef854726d083eb992d2020-04-01T00:00:00Zhttps://ejournal2.undip.ac.id/index.php/jbtr/article/view/5474https://doaj.org/toc/2503-2178Background: The vegan diet in children provides the benefit of reducing the risk of being overweight and improving the fat profile. The risk that can occur in the provision of a vegan diet in children is anthropometric size below reference and low caloric intake. Growth hormone (GH) and Insulin like Growth Factors (IGFs) are powerful stimulators for longitudinal growth of bone and require insulin-like growth factor binding protein (IGFBPs) which acts as a transport protein for IGF-1. A vegan diet with lower calorie intake in children has lower IGF-I levels than children with an omnivorous diet. Objective: Examining the effect of vegan diets on IGF-1 levels, IGFBP-3 levels, and growth velocity. Methods: This study was done with a prospective cohort design. The study subjects were divided into two groups, namely the vegan group and the omnivorous group, then matched based on age and sex. During the study, anthropometric data collection, IGF-1 and IGFBP-3 levels measurements were done in both vegan children and omnivorous children. Results: During 6 months of observation, 22 subjects were divided into two groups, namely children with a vegan diet and children with an omnivorous diet. IGF-1 (ng / mL) in vegan children was 105.5 ± 47.3 compared to 102.7 ± 42.3 in omnivorous children with a value of p = 0.89. IGFBP-3 (ng / mL) in vegan children was 2146.4 ± 595.1 compared to 2142 ± 609.1 in omnivorous children with value of p = 0.99 and Growth Velocity (cm / 6 months) was 3.0 in vegan children (1.0-5.30), and 3.2 (2.6-6.5) in omnivorous children with value of p = 0.41. Conclusion:Children with vegan diet had IGF-1 level, IGFBP-3 level, and growth velocity that were the same as children with an omnivorous diet.Arie PurwanaBudiono BudionoJose RL BatubaraMuhammad FaiziDiponegoro Universityarticleigf-1igfbp-3growth velocityMedicine (General)R5-920ENJournal of Biomedicine and Translational Research, Vol 6, Iss 1, Pp 6-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	igf-1 igfbp-3 growth velocity Medicine (General) R5-920
spellingShingle	igf-1 igfbp-3 growth velocity Medicine (General) R5-920 Arie Purwana Budiono Budiono Jose RL Batubara Muhammad Faizi Association of Growth Velocity with Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Children with a Vegan Diet
description	Background: The vegan diet in children provides the benefit of reducing the risk of being overweight and improving the fat profile. The risk that can occur in the provision of a vegan diet in children is anthropometric size below reference and low caloric intake. Growth hormone (GH) and Insulin like Growth Factors (IGFs) are powerful stimulators for longitudinal growth of bone and require insulin-like growth factor binding protein (IGFBPs) which acts as a transport protein for IGF-1. A vegan diet with lower calorie intake in children has lower IGF-I levels than children with an omnivorous diet. Objective: Examining the effect of vegan diets on IGF-1 levels, IGFBP-3 levels, and growth velocity. Methods: This study was done with a prospective cohort design. The study subjects were divided into two groups, namely the vegan group and the omnivorous group, then matched based on age and sex. During the study, anthropometric data collection, IGF-1 and IGFBP-3 levels measurements were done in both vegan children and omnivorous children. Results: During 6 months of observation, 22 subjects were divided into two groups, namely children with a vegan diet and children with an omnivorous diet. IGF-1 (ng / mL) in vegan children was 105.5 ± 47.3 compared to 102.7 ± 42.3 in omnivorous children with a value of p = 0.89. IGFBP-3 (ng / mL) in vegan children was 2146.4 ± 595.1 compared to 2142 ± 609.1 in omnivorous children with value of p = 0.99 and Growth Velocity (cm / 6 months) was 3.0 in vegan children (1.0-5.30), and 3.2 (2.6-6.5) in omnivorous children with value of p = 0.41. Conclusion:Children with vegan diet had IGF-1 level, IGFBP-3 level, and growth velocity that were the same as children with an omnivorous diet.
format	article
author	Arie Purwana Budiono Budiono Jose RL Batubara Muhammad Faizi
author_facet	Arie Purwana Budiono Budiono Jose RL Batubara Muhammad Faizi
author_sort	Arie Purwana
title	Association of Growth Velocity with Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Children with a Vegan Diet
title_short	Association of Growth Velocity with Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Children with a Vegan Diet
title_full	Association of Growth Velocity with Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Children with a Vegan Diet
title_fullStr	Association of Growth Velocity with Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Children with a Vegan Diet
title_full_unstemmed	Association of Growth Velocity with Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Children with a Vegan Diet
title_sort	association of growth velocity with insulin-like growth factor-1 and insulin-like growth factor binding protein-3 levels in children with a vegan diet
publisher	Diponegoro University
publishDate	2020
url	https://doaj.org/article/b767ba73f00d4cef854726d083eb992d
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Association of Growth Velocity with Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Children with a Vegan Diet

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