Exploring cell-specific miRNA regulation with single-cell miRNA-mRNA co-sequencing data

Exploring cell-specific miRNA regulation with single-cell miRNA-mRNA co-sequencing data

Abstract Background Existing computational methods for studying miRNA regulation are mostly based on bulk miRNA and mRNA expression data. However, bulk data only allows the analysis of miRNA regulation regarding a group of cells, rather than the miRNA regulation unique to individual cells. Recent ad...

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Bibliographic Details
Main Authors: Junpeng Zhang, Lin Liu, Taosheng Xu, Wu Zhang, Chunwen Zhao, Sijing Li, Jiuyong Li, Nini Rao, Thuc Duy Le
Format: article
Language:EN
Published: BMC 2021
Subjects:
miRNA
mRNA
Single-cell miRNA-mRNA co-sequencing
Pseudo-cell interpolation
Cell-specific miRNA regulation
Single-cell clustering analysis
Computer applications to medicine. Medical informatics
R858-859.7
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/b77154efc5954fb7be9a514def7e611a
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https://doaj.org/article/b77154efc5954fb7be9a514def7e611a

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